PCF11

  • Official Full Name

    PCF11, cleavage and polyadenylation factor subunit, homolog

  • Overview

    PCF11 (pre-mRNA cleavage complex 2 protein) plays a role in transcriptional termination. The gene for PCF11 is also known as KIAA0824.

  • Synonyms

    PCF11;PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae);PCF11, cleavage and polyadenylation factor II subunit, homolog (S. cerevisiae);pre-mRNA cleavage complex 2 protein Pcf11;KIAA0824;PCF11p homolog;pre-mRNA cleavage comp
Cat.# Product name Source (Host) Species Tag Protein Length Price
PCF11-1573H Recombinant Human PCF11, His-tagged E.coli Human His 1206-1555aa
PCF11-1700Z Recombinant Zebrafish PCF11 Mammalian Cell Zebrafish His

    Involved Pathway

    PCF11 involved in several pathways and played different roles in them. We selected most pathways PCF11 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA surveillance pathway PABPC1B,FIP1L1,NCBP1,NXT2,CPSF6,PPP2CB,WDR33,PPP2R5D,SYMPK,PPP1CC

    Protein Function

    PCF11 has several biochemical functions, for example, RNA polymerase II core binding,mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCF11 itself. We selected most functions PCF11 had, and list some proteins which have the same functions with PCF11. You can find most of the proteins on our site.

    Function Related Protein
    mRNA binding EIF4ENIF1,AGO2,TYMS,KHSRP,CSTF2,RBM5,RPS3,SOSTDC1B,LUC7L2,RBMX
    RNA polymerase II core binding RECQL5,KIAA1967,SMYD2A,KIAA1530,SMYD2B,PAF1,AGO1,ZNF326,SMYD2,WACA

    Interacting Protein

    PCF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCF11.

    Clp1;BNLF1;rpoB;q7ard3_yerpe;sSL2;trpE;sbcC3;AK1;Junb;USF1;MAPK3;CDK8;SNW1;EMC2;SAMD1;Cdkn2aip;MRPL50;CEP170P1;Rprd1b;CDKN2AIP

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