PCDHA10

  • Official Full Name

    protocadherin alpha 10

  • Overview

    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

  • Synonyms

    PCDHA10;protocadherin alpha 10;CNRS8;protocadherin alpha-10;CNR8;CNRN8;CRNR8;KIAA0345 like 4;ortholog to mouse CNR8;PCDH ALPHA10;PCDH-alpha-10;KIAA0345-like 4;PCDH-ALPHA10

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PCDHA10-2651H Recombinant Human PCDHA10 protein, His-tagged E.coli Human His 276-324 aa
PCDHA10-12429M Recombinant Mouse PCDHA10 Protein Mammalian Cells Mouse His
PCDHA10-3397HCL Recombinant Human PCDHA10 293 Cell Lysate HEK293 Human Non
PCDHA10-1907H Recombinant Human PCDHA10 Protein, His-tagged E.coli Human His Gln29-Pro219
PCDHA10-301195H Recombinant Human PCDHA10 protein, GST-tagged E.coli Human GST Met276-Lys324
PCDHA10-6540M Recombinant Mouse PCDHA10 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PCDHA10-6540M-B Recombinant Mouse PCDHA10 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PCDHA10 involved in several pathways and played different roles in them. We selected most pathways PCDHA10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCDHA10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    PCDHA10 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDHA10 itself. We selected most functions PCDHA10 had, and list some proteins which have the same functions with PCDHA10. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding SYT1B,SYT12,EFHA2,MFGE8A,DSG2,PCDH2G29,EMR1,NDUFAB1,CDH23,NKD2A

    Interacting Protein

    PCDHA10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCDHA10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCDHA10.

    CRK

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