PBRM1
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Official Full Name
polybromo 1 -
Overview
Protein polybromo-1 (PB1) also known as BRG1-associated factor 180 (BAF180) is a protein that in humans is encoded by the PBRM1 gene. -
Synonyms
PBRM1;polybromo 1;protein polybromo-1;BAF180;PB1;CG11375;MGC156155;MGC156156;OTTHUMP00000202149;OTTHUMP00000202150;OTTHUMP00000202151;OTTHUMP00000202153;OTTHUMP00000202163;polybromo-1D;BRG1-associated factor 180
Recombinant Proteins
- Human
- Chicken
- E.coli
- Mammalian Cells
- His
- His&Flag
- GST
- His&Strep
- Non
Involved Pathway
PBRM1 involved in several pathways and played different roles in them. We selected most pathways PBRM1 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,RMTs methylate histone arginines, which may be useful for your reference. Also, other proteins which involved in the same pathway with PBRM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromatin modifying enzymes | KANSL2,MSL3,TADA3,RBBP7,CHD4,C20orf20,MBD3A,SMYD2,EP400,SMARCC1B |
| RMTs methylate histone arginines | ARID1A,ACTL6B,PRMT7,PRMT5,PBRM1L,SMARCD1,WDR77,PRMT6,SMARCB1B,SMARCC2 |
| Chromatin organization | KDM3A,TADA2B,SUDS3,KDM4B,PHF20B,SUZ12B,RBBP5,CHD4,EED,BRD8 |
Protein Function
PBRM1 has several biochemical functions, for example, DNA binding,chromatin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PBRM1 itself. We selected most functions PBRM1 had, and list some proteins which have the same functions with PBRM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin binding | NKX2,SHMT2,MLH3,HOXC13,DNAJC2,ARX,MEOX1,PAX3,TFAP2A,PRDM13 |
| DNA binding | H2AFX,ZFML,FOXC1A,IMPDH1,ZNF512,MCM3,HIST1H4B,PAX4,UNCX4.1,ZNF41 |
| protein binding | HSPA1B,EFEMP2,KAT2B,ELK4,FAM58A,EXOC1,Icosl,TFF1,ZNF266,VAC14 |
Interacting Protein
PBRM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PBRM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PBRM1.
SMARCA4;ARID2;ACTL6A;PHB;SCHIP1;yopM;ZNF512B;SNW1;SMARCC2;ESR2;SMARCC1;SMARCE1;SMARCD1
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References
- Li, B; Qiu, B; et al. Fructose-1,6-bisphosphatase opposes renal carcinoma progression. NATURE 513:251-+(2014).
- Meier, K; Brehm, A; et al. Chromatin regulation: How complex does it get?. EPIGENETICS 9:1485-1495(2014).
