PALB2
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Official Full Name
partner and localizer of BRCA2 -
Overview
This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008] -
Synonyms
PALB2;partner and localizer of BRCA2;FANCN;PNCA3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PALB2-1516H | Recombinant Human PALB2, GST-tagged | E.coli | Human | GST | 841-1186aa | |
| PALB2-12324M | Recombinant Mouse PALB2 Protein | Mammalian Cells | Mouse | His |
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| PALB2-3451HCL | Recombinant Human PALB2 293 Cell Lysate | HEK293 | Human | Non |
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| PALB2-37H | Recombinant Human PALB2 Protein, His-tagged | E.coli | Human | His | 1-287 a.a. |
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| PALB2-6477M | Recombinant Mouse PALB2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PALB2-6477M-B | Recombinant Mouse PALB2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PALB2 involved in several pathways and played different roles in them. We selected most pathways PALB2 participated on our site, such as Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PALB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fanconi Anemia Pathway | HES1,MLH1,FANCB,FANCM,FANCL,RMI1,ERCC4,RAD51C,FANCA,RMI2 |
Protein Function
PALB2 has several biochemical functions, for example, DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PALB2 itself. We selected most functions PALB2 had, and list some proteins which have the same functions with PALB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | SET,ZFP593,SP4,ZNF559,ZSCAN4D,ZFP11,ZFML,CEBPZ,AHR,KLF7 |
| protein binding | RHOH,TET3,NR1I2,TPD52L3,MATN1,PCBD2,CLCNKB,MTA1,APOB,SPEF1 |
Interacting Protein
PALB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PALB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PALB2.
BRCA2;POLH
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