PAIP2
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Official Full Name
poly(A) binding protein interacting protein 2 -
Overview
The eukaryotic mRNA 3 poly(A) tail interacts with the 5 cap structure to regulate translation of mRNA transcripts. The eIF4G translation initiation factor associates with poly(A) binding protein (PABP) to circularize mRNA. Paip1 is a PABP interacting prot -
Synonyms
PAIP2;poly(A) binding protein interacting protein 2;polyadenylate-binding protein-interacting protein 2;PAIP2A;PAIP-2;PABP-interacting protein 2;PABC1-interacting protein 2;polyA-binding protein-interacting protein 2;poly(A)-binding protein-intera
Recombinant Proteins
- Mouse
- Chicken
- Human
- Rhesus macaque
- Rat
- Mammalian Cell
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
PAIP2 involved in several pathways and played different roles in them. We selected most pathways PAIP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAIP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PAIP2 has several biochemical functions, for example, mRNA binding,protein binding,translation repressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAIP2 itself. We selected most functions PAIP2 had, and list some proteins which have the same functions with PAIP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NFKBIA,GPR37,KIAA1530,XCL2,BIN1,LCP2,POLDIP2,ZNF239,STATH,SH2B3 |
| mRNA binding | CPSF5,AGO2,NOVA1,PIWIL2,SOSTDC1B,RC3H2,SNRNP35,TDRD7,SNRPC,LUC7L2 |
| translation repressor activity | IREB2,CIRBP,EIF4EBP3,PATL2,EIF4EBP2,SAMD4A,TRIM71,SAMD4,EIF4EBP1 |
Interacting Protein
PAIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAIP2.
PABPC1;UBR5;q59em9_human;RPL11;GABARAPL2
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References
- Wang, LJ; Hsu, CW; et al. Interactome-wide Analysis Identifies End-binding Protein 1 as a Crucial Component for the Speck-like Particle Formation of Activated Absence in Melanoma 2 (AIM2) Inflammasomes. MOLECULAR & CELLULAR PROTEOMICS 11:1230-1244(2012).
- Kelley, LC; Weed, SA; et al. Cortactin Is a Substrate of Activated Cdc42-Associated Kinase 1 (ACK1) during Ligand-induced Epidermal Growth Factor Receptor Downregulation. PLOS ONE 7:-(2012).
