OSBPL5
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Official Full Name
oxysterol binding protein-like 5 -
Overview
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. -
Synonyms
OSBPL5;oxysterol binding protein-like 5;oxysterol-binding protein-related protein 5;KIAA1534;ORP5;DKFZp586H1719;FLJ31948;OBPH1;OSBP related protein 5;Oxysterol binding protein homologue 1;Oxysterol binding protein like 5;Oxysterol binding protein related protein 5;ORP-5;OSBP-related protein 5;oxysterol-binding protein homolog 1;oxysterol-binding protein homologue 1
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- HEK293
- E.coli
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OSBPL5-12202M | Recombinant Mouse OSBPL5 Protein | Mammalian Cell | Mouse | His |
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| OSBPL5-3533HCL | Recombinant Human OSBPL5 293 Cell Lysate | HEK293 | Human | Non |
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| OSBPL5-3534HCL | Recombinant Human OSBPL5 293 Cell Lysate | HEK293 | Human | Non |
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| OSBPL5-202H | Recombinant Human OSBPL5 protein, His-tagged | E.coli | Human | His | 1-353 aa |
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| Osbpl5-4611M | Recombinant Mouse Osbpl5 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| OSBPL5-4924H | Recombinant Human OSBPL5 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| OSBPL5-6413M | Recombinant Mouse OSBPL5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| OSBPL5-6413M-B | Recombinant Mouse OSBPL5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
OSBPL5 involved in several pathways and played different roles in them. We selected most pathways OSBPL5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OSBPL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
OSBPL5 has several biochemical functions, for example, cholesterol binding,oxysterol binding,phosphatidylinositol-4-phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OSBPL5 itself. We selected most functions OSBPL5 had, and list some proteins which have the same functions with OSBPL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phospholipid transporter activity | OSBPL8,MTTP,ABCA4,CETP,APOA1,ABCA7,GLTPD1,MFSD2AB,MFSD2A,ATP8B5 |
| phosphatidylinositol-4-phosphate binding | CLSTN2,OSBPL8,ARFIP1,LANCL2,PLEKHA8,GOLPH3L,D6WSU116E,SNX3,OSBP,COL4A3BP |
| phosphatidylserine binding | TRIM72,JPH2,PLCD1,FCHO2,SYTL2,OSBPL10,GAP43,RASGRP1,CPNE6,SDPR |
| cholesterol binding | SYP,STARD3,APOEA,OSBPL10,APOEB,ANXA6,PMP2,ABCA1,APOA4A,OSBPL8 |
| oxysterol binding | OSBP,GPR183,RORA,RORC |
Interacting Protein
OSBPL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSBPL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of OSBPL5.
ABL1;RIOK3;IPO8;MAGEA1;LIMK1;Sesn2;YWHAH;LRIF1;Samm50;Mus81;KIFC3;Cd2ap;KLC4;CDC23;ZNF281
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