OR8A1

  • Official Full Name

    olfactory receptor, family 8, subfamily A, member 1
  • Overview

    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
  • Synonyms

    OR8A1;olfactory receptor, family 8, subfamily A, member 1;olfactory receptor 8A1;OST025;Olfactory receptor OR11-318;OR11-318
Cat.# Product name Source (Host) Species Tag Protein Length Price
OR8A1-3555HCL Recombinant Human OR8A1 293 Cell Lysate HEK293 Human Non
RFL11767HF Recombinant Full Length Human Olfactory Receptor 8A1(Or8A1) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-326)

    Involved Pathway

    OR8A1 involved in several pathways and played different roles in them. We selected most pathways OR8A1 participated on our site, such as Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OR8A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Olfactory transduction OR2H1,OR51B5,OR1L6,OLFR486,OLFR492,OLFR473,OR5V1,OR2C1,PDC,OLFR498

    Protein Function

    OR8A1 has several biochemical functions, for example, G-protein coupled receptor activity,odorant binding,olfactory receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OR8A1 itself. We selected most functions OR8A1 had, and list some proteins which have the same functions with OR8A1. You can find most of the proteins on our site.

    Function Related Protein
    odorant binding OLFR493,OLFR470,OLFR477,OLFR181,OLFR1440,OLFR497,OR8B8,OR5H1,OBP2A,OR10J1
    G-protein coupled receptor activity TAAR7D,OR10H1,RXFP2B,EMR1,FZD7A,TAS2R136,HTR1AA,PTAFR,ADORA2AB,OR2A4
    olfactory receptor activity OR52J3,OR10C1,OR52B4,OLFR488,OLFR495,OR10W1,OLFR1013,OLFR1440,OR56A1,OR1L6

    Interacting Protein

    OR8A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OR8A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OR8A1.

    Resources

    References

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