OR2A4
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Official Full Name
olfactory receptor, family 2, subfamily A, member 4 -
Overview
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. -
Synonyms
OR2A4;olfactory receptor, family 2, subfamily A, member 4;olfactory receptor, family 2, subfamily A, member 10 , OR2A10;olfactory receptor 2A4;olfactory receptor 2A10;olfactory receptor OR6-37;olfactory receptor, family 2, subfamily A, member 10;OR2A10
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OR2A4-3565HCL | Recombinant Human OR2A4 293 Cell Lysate | HEK293 | Human | Non |
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| RFL1308HF | Recombinant Full Length Human Olfactory Receptor 2A4(Or2A4) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-310) |
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Involved Pathway
OR2A4 involved in several pathways and played different roles in them. We selected most pathways OR2A4 participated on our site, such as Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OR2A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Olfactory transduction | OLFR477,OLFR151,PDC,PDE1A,OLFR491,OLFR1440,OLFR1002,OR12D3,OLFR958,OLFR480 |
Protein Function
OR2A4 has several biochemical functions, for example, G-protein coupled receptor activity,molecular_function,olfactory receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OR2A4 itself. We selected most functions OR2A4 had, and list some proteins which have the same functions with OR2A4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| olfactory receptor activity | OLFR508,OLFR473,OR6Q1,OR2B3,OR1L6,OLFR998,OR56A1,OLFR688,OR51B5,OR51B4 |
| transmembrane signaling receptor activity | CLEC1B,GPR98,TLR4,CD5,PTH1RB,NFAM1,CD3D,NRXN3,KLRC2,KLRC1 |
| molecular_function | VSTM2B,CDCA7A,AKIRIN1,KHDC1C,ACBD5,TMEM167,CCDC14,GPM6B,CEP55L,LPAR6 |
| G-protein coupled receptor activity | OR4C13,TAS2R104,ZFPM2B,V2RX1,GPR183B,OR2K2,TAAR12E,GPR179,TAAR14E,OR2C1 |
Interacting Protein
OR2A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OR2A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of OR2A4.
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References
- Jahromi, MM; et al. Haplotype specific alteration of diabetes MHC risk by olfactory receptor gene polymorphism. AUTOIMMUNITY REVIEWS 12:270-274(2012).
- Zhang, X; Bedigian, AV; et al. G protein-coupled receptors participate in cytokinesis. CYTOSKELETON 69:810-818(2012).
