OPRM1
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Official Full Name
opioid receptor, mu 1 -
Overview
The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. -
Synonyms
OPRK1;K-OR-1;Kappa type opioid receptor;Kappa-type opioid receptor;KOR 1;KOR;KOR-1;Opiate receptor kappa 1;OPRK 1;OPRK;OPRK_HUMAN;Oprk2;R21;opioid receptor, kappa 1;OTTHUMP00000226313;Opioid Receptor, kappa;OTTHUMP00000226316;kappa opioid receptor;Opiate receptor, kappa-1
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Cynomolgus
- Zebrafish
- Human
- Pan troglodytes
- Guinea pig
- Mus musculus
- Bovine
- Macaca fascicularis
- Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
- Sus scrofa (Pig)
- Macaca mulatta
- Mammalian Cell
- HEK293
- E.coli
- HEK293T
- In vitro E. coli expression system
- Mammalian cells
- E.coli expression system
- His
- His&Flag
- His&Fc&Avi
- Myc&DDK
- GST
- Flag
Involved Pathway
OPRM1 involved in several pathways and played different roles in them. We selected most pathways OPRM1 participated on our site, such as Neuroactive ligand-receptor interaction,Estrogen signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPRM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Estrogen signaling pathway | GRM1,PIK3CB,MAPK3,AKT1,GNAS,PLCB4,KCNJ5,Adcy4,GRB2,HRAS |
| Neuroactive ligand-receptor interaction | LEPR,TAAR7D,SSTR1,GABRG1,GRM5,SSTR4,VIPR1B,UTS2R,PRLHR,FPR2 |
Protein Function
OPRM1 has several biochemical functions, for example, G-protein alpha-subunit binding,G-protein beta-subunit binding,G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPRM1 itself. We selected most functions OPRM1 had, and list some proteins which have the same functions with OPRM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BBS2,IK,PAK2,MRPL40,HSP90AA1.2,MAGEA8,SUMO1,ORAI2,VPS54,HIST1H4B |
| neuropeptide binding | NPBWR2,OPRD1,OPRK1,SSTR1,OPRD1A,MRGPRB1,NPBWR1,NPY8BR,MC4R,NPY8AR |
| G-protein alpha-subunit binding | F2RL1,DRD1A,LPAR1,RIC8,IGF1R,ADRB2,PPP5C,F2R,RIC8A,AGTR1A |
| G-protein coupled receptor activity | TAS2R107,COR6,TAAR8B,GPR173,OLFR146,TAS2R129,TAAR2,OPN3,Fzd4,APLNR |
| voltage-gated calcium channel activity | CACNA2D1,CACNA2D2,ITGAV,CACNA1BA,CACNG7,ATP6V0CB,CACNB2B,GAS6,CATSPER3,CACNG2 |
| G-protein beta-subunit binding | GNG2,RGS7,RGS11,GNG13,F2R,RASD2,RGS9,F2RL1,CCT5 |
Interacting Protein
OPRM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPRM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPRM1.
WLS;RANBP9;FLNA
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