OPRK1
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Official Full Name
opioid receptor, kappa 1 -
Overview
The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood. -
Synonyms
OPRK1;K-OR-1;Kappa type opioid receptor;Kappa-type opioid receptor;KOR 1;KOR;KOR-1;Opiate receptor kappa 1;OPRK 1;OPRK;OPRK_HUMAN;Oprk2;R21;opioid receptor, kappa 1;OTTHUMP00000226313;Opioid Receptor, kappa;OTTHUMP00000226316;kappa opioid receptor;Opiate receptor, kappa-1
Recombinant Proteins
- Mouse
- Human
- Rat
- Zebrafish
- Bovine
- Mus musculus
- Guinea pig
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli expression system
- His
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
OPRK1 involved in several pathways and played different roles in them. We selected most pathways OPRK1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OPRK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | GRM2,MC4R,LEPR,Chrng,GRIK4,FSHR,P2RX4A,DRD7,CHRNB4,TACR1 |
Protein Function
OPRK1 has several biochemical functions, for example, dynorphin receptor activity,neuropeptide binding,opioid receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OPRK1 itself. We selected most functions OPRK1 had, and list some proteins which have the same functions with OPRK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| opioid receptor activity | OPRD1A,NPBWR1,OGFR,OPRD1B,SIGMAR1,OPRD1,NPBWR2 |
| protein binding | BCL9,SERBP1,GSDMA2,NABP1,UNG,TNFRSF10B,FAM54B,RAB39B,PLEKHA2,RPS28 |
| neuropeptide binding | MC3R,GALR1,OPRL1,SSTR1,MRGPRX2,NPY8AR,OPRM1,ADCYAP1R1,OPRD1B,NPBWR2 |
Interacting Protein
OPRK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OPRK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OPRK1.
GABARAPL1;GPRASP1;u69593;u50488;SLC9A3R1;SIAH2;GJA4;WLS;SIAH1;VAPA;AUP1;GABARAP;GABARAPL1
Resources
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References
- Faisal, M; Waseem, D; et al. A molecular prospective provides new insights into implication of PDYN and OPRK1 genes in alcohol dependence. COMPUTERS IN BIOLOGY AND MEDICINE 53:250-257(2014).
- Trescot, AM; Faynboym, S; et al. A Review of the Role of Genetic Testing in Pain Medicine. PAIN PHYSICIAN 17:425-445(2014).
