ONECUT1
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Official Full Name
one cut homeobox 1 -
Overview
The protein encoded by HNF6 is Transcriptional activator. Binds the consensus sequence 5-DHWATTGAYTWWD-3 on a varietyof gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. -
Synonyms
ONECUT1;one cut homeobox 1;HNF6, HNF6A, one cut domain, family member 1;hepatocyte nuclear factor 6;HNF 6;one cut domain family member 1;one cut domain, family member 1;hepatocyte nuclear factor 6, alpha;HNF6;HNF-6;HNF6A
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E. coli
- GST
- His
- Non
- His&GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ONECUT1-1458H | Recombinant Human ONECUT1, GST-tagged | E.coli | Human | GST | 167-292aa | |
| ONECUT1-10852Z | Recombinant Zebrafish ONECUT1 | Mammalian Cell | Zebrafish | His |
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| ONECUT1-12153M | Recombinant Mouse ONECUT1 Protein | Mammalian Cell | Mouse | His |
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| ONECUT1-128H | Recombinant Human ONECUT1 | E.coli | Human | Non |
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| ONECUT1-29373TH | Recombinant Human ONECUT1 | E.coli | Human | Non | 465 amino acids |
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| ONECUT1-4186R | Recombinant Rat ONECUT1 Protein | Mammalian Cell | Rat | His |
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| ONECUT1-3576HCL | Recombinant Human ONECUT1 293 Cell Lysate | HEK293 | Human | Non |
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| ONECUT1-1459H | Recombinant Human ONECUT1 protein, His-tagged | E. coli | Human | His | 167-292 aa |
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| ONECUT1-23HFL | Recombinant Full Length Human ONECUT1 Protein, His&GST tagged | E.coli | Human | His&GST | Full L. 1-465aa |
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| ONECUT1-3848R | Recombinant Rat ONECUT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ONECUT1-3848R-B | Recombinant Rat ONECUT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ONECUT1-6391M | Recombinant Mouse ONECUT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ONECUT1-6391M-B | Recombinant Mouse ONECUT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ONECUT1 involved in several pathways and played different roles in them. We selected most pathways ONECUT1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells,Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with ONECUT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling pathways regulating pluripotency of stem cells | WNT6,FZD7,BMP4,WNT2,FGFR1,PAX6,MAPK12,PIK3CD,AKT1,SOX2 |
| Maturity onset diabetes of the young | NEUROG3,HHEX,INS2,RFX6,INS,IAPP,HNF4G,FOXA2,HNF4A,HES1 |
Protein Function
ONECUT1 has several biochemical functions, for example, DNA binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ONECUT1 itself. We selected most functions ONECUT1 had, and list some proteins which have the same functions with ONECUT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | SIX7,SMAD9,ZNF781,SIX4B,JUNBB,TOPBP1,HDX,FOXQ2,GTF2I,FOXD1 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | MZF1,ONECUT3,POU2F2,TP63,WT1,MITFA,PAX8,SFPI1,TFAP2C,PITX3 |
Interacting Protein
ONECUT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ONECUT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ONECUT1.
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