OLFR49
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Official Full Name
olfactory receptor 49 -
Overview
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. -
Synonyms
OLFR49;olfactory receptor 49;Olfactory receptor MOR118 1;IC6;Olfactory receptor;MOR1181
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OLFR49-11738M | Recombinant Mouse OLFR49 Protein | Mammalian Cell | Mouse | His |
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| OLFR49-6368M | Recombinant Mouse OLFR49 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| OLFR49-6368M-B | Recombinant Mouse OLFR49 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
OLFR49 involved in several pathways and played different roles in them. We selected most pathways OLFR49 participated on our site, such as Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OLFR49 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Olfactory transduction | OLFR478,PRKG1,OLFR1440,OLFR508,OR52J3,OR2L5,OR51B5,OLFR958,CALML5,OR7C1 |
Protein Function
OLFR49 has several biochemical functions, for example, G-protein coupled receptor activity,isoprenoid binding,olfactory receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OLFR49 itself. We selected most functions OLFR49 had, and list some proteins which have the same functions with OLFR49. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| olfactory receptor activity | OR6B2,OR2A42,OR11A1,OLFR8,OR2A4,OLFR470,OR2L5,OR10H1,OR7C1,OR52B4 |
| isoprenoid binding | OLFR50,FNTB |
| G-protein coupled receptor activity | OXGR1A.3,GPR143,GPRC6A,CD97,GRM6,OLFCG3,TAS2R107,OLFR469,TM2D1,GPR110 |
| signal transducer activity | LPAR6,F2RL2,OLFR1440,AKAP13,GHRHR2,PPFIA1,OPN4XB,FPR-RS6,FAS,TAAR12H |
Interacting Protein
OLFR49 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OLFR49 here. Most of them are supplied by our site. Hope this information will be useful for your research of OLFR49.
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References
- Brandes, G; Khayami, M; et al. Cell surface expression of 27C7 by neonatal rat olfactory ensheathing cells in situ and in vitro is independent of axonal contact. HISTOCHEMISTRY AND CELL BIOLOGY 135:397-408(2011).
- Kawagishi, K; Yokouchi, K; et al. Determination of functionally essential neuronal population of the olfactory epithelium for nipple search and subsequent suckling behavior in newborn rats. BRAIN RESEARCH 1276:50-57(2009).
