OLFR2
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Official Full Name
olfactory receptor 2 -
Overview
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. -
Synonyms
OLFR2;olfactory receptor 2;I54;I7 olfactory receptor;MOR103 15;Olfr41;OR2H3;odorant receptor B2;olfactory receptor 41;GA_x6K02T2PBJ9-9381439-9380456;I7;MOR103-15
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Involved Pathway
OLFR2 involved in several pathways and played different roles in them. We selected most pathways OLFR2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OLFR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
OLFR2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by OLFR2 itself. We selected most functions OLFR2 had, and list some proteins which have the same functions with OLFR2. You can find most of the proteins on our site.
Function | Related Protein |
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Interacting Protein
OLFR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OLFR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OLFR2.
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References
- Irwin, M; Greig, A; et al. PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb. JOURNAL OF NEUROPHYSIOLOGY 113:1234-1248(2015).
- Takahashi, K; Kurihara, Y; et al. Association of Cerebrospinal Fluid Levels of Lateral Olfactory Tract Usher Substance (LOTUS) With Disease Activity in Multiple Sclerosis. JAMA NEUROLOGY 72:176-179(2015).