OASL
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Official Full Name
2-5-oligoadenylate synthetase-like -
Overview
59 kDa 2-5-oligoadenylate synthetase-like protein is an enzyme that in humans is encoded by the OASL gene. -
Synonyms
OASL;2-5-oligoadenylate synthetase-like;59 kDa 2-5-oligoadenylate synthase-like protein;p59OASL;TRIP14;TRIP-14;p59 OASL;TR-interacting protein 14;thyroid receptor-interacting protein 14;59 kDa 2-5-oligoadenylate synthetase-like protein
Recombinant Proteins
- Human
- Rat
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OASL-310H | Recombinant Human OASL Protein, His-tagged | E.coli | Human | His | Ala2~Trp244 | |
| OASL-4146R | Recombinant Rat OASL Protein | Mammalian Cells | Rat | His |
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| OASL-521H | Recombinant Human OASL Protein, His-tagged | E.coli | Human | His |
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| OASL-6598C | Recombinant Chicken OASL | Mammalian Cells | Chicken | His |
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| OASL-3612HCL | Recombinant Human OASL 293 Cell Lysate | HEK293 | Human | Non |
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| OASL-3808R | Recombinant Rat OASL Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| OASL-3808R-B | Recombinant Rat OASL Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| OASL-4533H | Recombinant Human OASL protein, His&Myc-tagged | E.coli | Human | His&Myc | 2-514aa |
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| OASL-4543H | Recombinant Human OASL protein, His-tagged | E.coli | Human | His | 2-514aa |
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| OASL-5229H | Recombinant Human OASL Protein (Met1-His100), C-His tagged | E.coli | Human | His | Met1-His100 |
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| OASL-5230H | Recombinant Human OASL Protein (Met1-Trp244), N-His tagged | E.coli | Human | His | Met1-Trp244 |
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Involved Pathway
OASL involved in several pathways and played different roles in them. We selected most pathways OASL participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with OASL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Interferon Signaling | IFIT2,GBP5,TRIM62,FCGR1B,IRF6,TRIM14,IFIT3,TRIM38,EIF4G2A,BST2 |
| Immune System | CD160,CHST13,IFI6,PPAPDC1B,PELI2,CTS7,MYO9B,DDOST,NLRP4,PAG1 |
| Interferon alpha/beta signaling | IFI27,IRF2,BST2,IRF4,IFI35,IRF9,GBP2,USP18,IRF6,IFITM2 |
| Cytokine Signaling in Immune system | IFI6,GBP5,TNFRSF13C,GBP1,SPTA1,HBEGF,MARK3,TNFSF13B,MAP3K8,DAB2IPB |
| Interferon gamma signaling | TRIM2,FCGR1B,TRIM10,TRIM3,TRIM38,TRIM17,GBP6,TRIM26,TRIM22,TRIM29 |
Protein Function
OASL has several biochemical functions, for example, NOT 2-5-oligoadenylate synthetase activity,ATP binding,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OASL itself. We selected most functions OASL had, and list some proteins which have the same functions with OASL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | TRAP1,DDX28,BTK,TNIK,ILF2,CLP1,CLCN4-2,Abca2,AARS2,POMK |
| poly(A) RNA binding | EIF3C,NGRN,NKRF,SAMSN1,RBM6,HLTF,DAP3,MYH9,QKI,ZMAT3 |
| DNA binding | ETV5A,ZNF689,HOXB9A,TRERF1,ZFP422,POLR1D,CLOCKA,HIST1H2BA,POLR3A,FOXS1 |
| double-stranded RNA binding | VIM,LSM14A,SLC3A2,DHX58,EIF4A1,ILF2,OAS2,LRRFIP1,EIF2C3,YRDC |
| NOT 2-5-oligoadenylate synthetase activity | OAS1B,OASL1 |
| thyroid hormone receptor binding | MED12,NCOR1,THRAP3,MED30,MED13,MED17,MED24,TRIP6,TAF11,NCOA3 |
Interacting Protein
OASL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OASL here. Most of them are supplied by our site. Hope this information will be useful for your research of OASL.
SEZ6L2;CD14;Map9;TMEM63B;Spire2;Klc3;TM9SF4;SORT1
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References
- Feng, XB; Huang, J; et al. Identification of interferon-inducible genes as diagnostic biomarker for systemic lupus erythematosus. CLINICAL RHEUMATOLOGY 34:71-79(2015).
- Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
