O3FAR1
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Official Full Name
omega-3 fatty acid receptor 1 -
Overview
GPR120 is a member of the rhodopsin family of G protein-coupled receptors (GPRs). This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
GT01;PGR4;GPR120;GPR129;MGC119984;DKFZp686F0824;omega-3 fatty acid receptor 1;OTTHUMP00000032309;OTTHUMP00000032310;G protein-coupled receptor 120;G protein-coupled receptor 129;G-protein coupled receptor 120;G-protein coupled receptor 129;G protein-coupled receptor PGR4;G-protein coupled receptor GT01;G-protein coupled receptor PGR4;G-protein-coupled receptor GT01;omega-3 fatty acid receptor 1;O3FAR1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| O3FAR1-4140R | Recombinant Rat O3FAR1 Protein | Mammalian Cell | Rat | His |
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| O3FAR1-3802R | Recombinant Rat O3FAR1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| O3FAR1-3802R-B | Recombinant Rat O3FAR1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
O3FAR1 involved in several pathways and played different roles in them. We selected most pathways O3FAR1 participated on our site, such as Incretin synthesis, secretion, and inactivation,Metabolism of proteins,Non-odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with O3FAR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | TSSK5,RAVER1,PKD1,OASL2,FRAS1,CARF,SLC6A2,ATP9A,FLII,TENC1 |
| Peptide hormone metabolism | SLC30A5,DPP4,CPE,GRP,SLC30A8,BCHE,ATP6AP2,CMA1,PCSK2,CPA3 |
| Non-odorant GPCRs | OPN3,CELSR1,BAI2,EMR4,GPR132,RRH,GPR15,CELSR3 |
| Metabolism of proteins | GALNT13,PHC2,MUC4,ADAMTS13,SSPO,IGFBP2B,SEC23IP,LTF,MCFD2,SLC25A12 |
| Incretin synthesis, secretion, and inactivation | SPCS3,PCSK1,SLC38A8,GPR119,GPR120,GRP,CDX2,DPP4 |
Protein Function
O3FAR1 has several biochemical functions, for example, G-protein coupled receptor activity,fatty acid binding,lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by O3FAR1 itself. We selected most functions O3FAR1 had, and list some proteins which have the same functions with O3FAR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| taste receptor activity | GPR120,TAS2R134,TAS2R137,TAS2R140,TAS2R108,TAS1R1,TAS2R144,TAS2R138,TAS2R143,TAS2R7 |
| signal transducer activity | TRAF5,CRKL,ECT2,TACR1A,MC5RA,MRGPRB5,TAS2R124,PRMT2,RGRB,MIER1A |
| fatty acid binding | ADH5,LBFABP,FABP1,NDUFAB1,FABP4,FABP2,ACOX2,Alb,CYP4A14,HNF4A |
| G-protein coupled receptor activity | OLFR13,OR7C1,DRD4A,GLP2R,OPN3,HTR1D,GPR63,OXGR1A.2,Fzd4,FZD1 |
| protein binding | MOBP,ELF1,FMO4,SSX1,PAFAH1B3,ARRB2,NPHS1,DIS3L2,HENMT1,CRYAA |
| lipid binding | APOA1A,EPN1,EPN2,SH3GL1,COQ9,RASGRP1,ACBD7,PAQR5A,PTEN,EPN3 |
Interacting Protein
O3FAR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with O3FAR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of O3FAR1.
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References
- Fontanesi, L; Bertolini, F; et al. Next Generation Semiconductor Based-Sequencing of a Nutrigenetics Target Gene (GPR120) and Association with Growth Rate in Italian Large White Pigs. ANIMAL BIOTECHNOLOGY 26:92-97(2015).
- Lager, S; Ramirez, VI; et al. Expression and localization of the omega-3 fatty acid receptor GPR120 in human term placenta. PLACENTA 35:523-525(2014).
