NXF5
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Official Full Name
nuclear RNA export factor 5 -
Overview
This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. -
Synonyms
NXF5;nuclear RNA export factor 5;TAPL-1;TAP-like protein 1
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Involved Pathway
NXF5 involved in several pathways and played different roles in them. We selected most pathways NXF5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NXF5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
NXF5 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NXF5 itself. We selected most functions NXF5 had, and list some proteins which have the same functions with NXF5. You can find most of the proteins on our site.
Function | Related Protein |
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Interacting Protein
NXF5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NXF5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NXF5.
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References
- Katahira, J; Okuzaki, D; et al. Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I. NUCLEIC ACIDS RESEARCH 41:7060-7072(2013).
- Shola, DTN; Wang, H; et al. Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8. ONCOGENE 31:2480-2490(2012).