NXF2

  • Official Full Name

    nuclear RNA export factor 2

  • Overview

    This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.

  • Synonyms

    NXF2;nuclear RNA export factor 2;cancer/testis antigen 39;CT39;TAP like protein 2;TAPL 2;FLJ20416;TAPL2;OTTHUMP00000023710;OTTHUMP00000023711;OTTHUMP00000023712;TAP-like protein 2;t-complex protein 11 homolog;NXF2B;TAPL-2
Cat.# Product name Source (Host) Species Tag Protein Length Price
NXF2-3621HCL Recombinant Human NXF2 293 Cell Lysate HEK293 Human Non
Nxf2-1874M Recombinant Mouse Nxf2 Protein, His-tagged E.coli Mouse His Leu454-Lys685
NXF2-1977H Recombinant Human NXF2 Protein, His-tagged E.coli Human His
NXF2-2520H Recombinant Human NXF2 Protein, His-tagged E.coli Human His Leu391-Ser625
nxf2-643F Recombinant Fruit fly nxf2 protein, His&Myc-tagged E.coli Fruit fly N-His&C-Myc 573-841aa
nxf2-7432F Recombinant Fruit fly nxf2 protein, His-tagged Insect cells Fruit fly His 573-841aa

    Involved Pathway

    NXF2 involved in several pathways and played different roles in them. We selected most pathways NXF2 participated on our site, such as Ribosome biogenesis in eukaryotes,RNA transport,mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NXF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Herpes simplex infection CUL1A,NXF1,HLA-DMA,IFNA16,EIF2AK2,Hc,STAT1A,HNRNPK,C3A.2,MYD88
    Ribosome biogenesis in eukaryotes DKC1,RRP7A,RAN,LOC81691,EMG1,RIOK2,POP7,XRN1,IMP3,BMS1
    mRNA surveillance pathway PABPC1,PABPN1,MAGOH,ETF1,NCBP1,UPF3B,PABPC3,WIBG,PPP2R5EA,PPP2R2CA
    Influenza A HLA-DPA1,RELA,RAE1,CPSF4,EIF2AK3,CXCL8,XPO1,HSPA8,TNFRSF10C,FASLG
    RNA transport EIF3BA,SUMO3,THOC1,EIF4G1A,NUP37,PABPC1A,THOC3,POM121L2,CYFIP2,EIF4E1B

    Protein Function

    NXF2 has several biochemical functions, for example, mRNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NXF2 itself. We selected most functions NXF2 had, and list some proteins which have the same functions with NXF2. You can find most of the proteins on our site.

    Function Related Protein
    nucleotide binding RTCB,RAB34A,EPHA2A,SF3B4,TRA2A,KIF4,HDGF,NOL8,SGK2A,ATP11A
    protein binding NATD1,PCBD1,FBXO11,Chrng,IRF1,AP2B1,SAP30L,CNOT2,STX5,POLR3GL
    mRNA binding XPO5,EIF4A1,PAIP2,G3BP1,ESRP1,QKI,RPS26,D19BWG1357E,DHFRL1,EIF4ENIF1
    poly(A) RNA binding ARL6IP4,BST2,PRAC,FASTKD3,HMGB3,DDX23,PA2G4,RP9,SAP18,MYO5A

    Interacting Protein

    NXF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NXF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NXF2.

    Nxt1

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