NVL
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Official Full Name
nuclear VCP-like -
Overview
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. -
Synonyms
NVL;nuclear VCP-like;nuclear valosin-containing protein-like;Nuclear valosin containing protein like;nuclear VCP like protein;Nuclear VCP like;Nuclear VCP-like protein;NVL_HUMAN;NVLp;OTTHUMP00000035641;OTTHUMP00000216593;OTTHUMP00000216594;OTTHUMP00000216599;OTTHUMP00000216600
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- HEK293T
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NVL-1426H | Recombinant Human NVL, His-tagged | E.coli | Human | His | C-term-351aa | |
| NVL-11012M | Recombinant Mouse NVL Protein | Mammalian Cell | Mouse | His |
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| NVL-12649Z | Recombinant Zebrafish NVL | Mammalian Cell | Zebrafish | His |
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| NVL-30495TH | Recombinant Human NVL, His-tagged | E.coli | Human | His | 431-734 a.a. |
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| NVL-3546C | Recombinant Chicken NVL | Mammalian Cell | Chicken | His |
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| NVL-1237HCL | Recombinant Human NVL cell lysate | Human | Non |
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| NVL-1855H | Recombinant Human NVL Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| NVL-1972H | Recombinant Human NVL Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Nvl-4561M | Recombinant Mouse Nvl Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| NVL-5695H | Recombinant Human NVL Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| NVL-6284M | Recombinant Mouse NVL Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NVL-6284M-B | Recombinant Mouse NVL Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NVL involved in several pathways and played different roles in them. We selected most pathways NVL participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with NVL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | POP1,TBL3,POP5,NXF3,RPP25L,HEATR1,NMD3,RPP38,FBLL1,SPATA5 |
Protein Function
NVL has several biochemical functions, for example, ATP binding,poly(A) RNA binding,preribosome binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NVL itself. We selected most functions NVL had, and list some proteins which have the same functions with NVL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | SRRT,ZNF622,GPATCH4,SPATS2L,CIRH1A,SAMD4A,SUPT6H,POLRMT,ZCCHC6,BOP1 |
| protein binding | CCDC94,OPRD1,MAP3K1,SNX2,GNMT,PPEF1,PPP1R12C,GPR128,TBP,APBA3 |
| ATP binding | UBE2D1,DNAJA2,MVDA,NME2B.1,TAOK3,DDX6,PFKFB2A,AK8,TRPV1,COASY |
Interacting Protein
NVL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NVL here. Most of them are supplied by our site. Hope this information will be useful for your research of NVL.
HSPB1;UBE2I;CRMP1;OSGEP;TTF2;Srp72;NPM1;UBA1;RPL10;MNDA;CLCN2;RHOA;Cry1;HNRNPU;IFI16;q6t424_human;KIF21A;Rrbp1;Rbm8a;Tmed2
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