NUP35

  • Official Full Name

    nucleoporin 35kDa

  • Overview

    This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.

  • Synonyms

    NUP35;nucleoporin 35kDa;nucleoporin NUP53;MP44;35 kDa nucleoporin;Mitotic phosphoprotein 44;MP 44;NP 44;NP44;Nuclear pore complex protein 53kDa;Nuclear pore complex protein Nup 53;Nuclear pore complex protein Nup53;Nuclear pore protein NUP 53;Nuclear pore protein NUP53;Nucleoporin 53kDa;Nucleoporin Nup 35;Nucleoporin NUP 53;Nucleoporin Nup35;NUP 35;Nup 53;MP-44;NUP53

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Human
  • Rhesus macaque
  • Rat
  • Mammalian Cell
  • E.coli
  • HEK293
  • HEK293T
  • His
  • His&T7
  • Non
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    NUP35 involved in several pathways and played different roles in them. We selected most pathways NUP35 participated on our site, such as Antiviral mechanism by IFN-stimulated genes,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP35 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular responses to stress KDM6B,HSBP1B,CHMP4C,AMBRA1,ST13,DNAJB6,ATG9A,TNIK,EGLN2,PHC3
    Cell Cycle, Mitotic CP110,ENSA,CDKN2C,HIST3H2BB,SET,DYRK1A,SPC25,GMNN,NDEL1,B9D2
    Cell cycle MYCA,MCM7,THRSP,ORC2,CENPK,CENPC1,RAD9B,CDC14A,CDT1,CDC14AA
    Export of Viral Ribonucleoproteins from Nucleus NUPL2,DPF1,NUP50
    Cellular response to heat stress DNAJC7,DNAJC2,DNAJB6,RPS19BP1,HSPA7,KIAA1967,PTGES3,NUPL2,HSPA13,C11orf73
    Antiviral mechanism by IFN-stimulated genes UBE2L6,USP18,EIF4EB,IFIT10,EIF4A2,EIF4E,KPNA4,JAK1,IFIT11,DPF1
    Disease OPN1MW2,HMGA1,MTRR,MMADHC,TCEB3,CCNC,AP2S1,TH1L,CYP11A1,NPM1
    Cytokine Signaling in Immune system RASGRP1,WDR83,KPNA3,TRIM17,DUSP4,EDAR,FGFR1B,FRS2B,IFI35,IRAK3

    Protein Function

    NUP35 has several biochemical functions, for example, nucleocytoplasmic transporter activity,phospholipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP35 itself. We selected most functions NUP35 had, and list some proteins which have the same functions with NUP35. You can find most of the proteins on our site.

    Function Related Protein
    phospholipid binding PSD4,WDFY4,SNCA,SGIP1,PTAFR,MTAP1B,PLEKHA3,ANXA9,APOM,PACSIN1
    protein binding RGS2,SPRTN,PURA,PEX2,POC1A,LYRM2,PIH1D1,CDC42EP2,GRM6,ATP5F1
    single-stranded DNA binding ANXA1,YBX1,BLM,POLR2G,RAD51D,PURB,C10orf2,RPA3,TDP2,XRCC2
    nucleocytoplasmic transporter activity NUPL1,TPR,NUP54,UPF3A,NUP160,NUP133,RBM22,NUP214,TPRB,XPO1

    Interacting Protein

    NUP35 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP35 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP35.

    KCTD9;saicar;PKM;AHCTF1;v-bcl-2;Kifc5b;NUP153;NUP107;UBE2I;Ube2i;KPNB1;Nup98;Nup214;Nup107;Rcc1;SEH1L;Nup155;NUPL1

    Resources

    References

    • Eisenhardt, N; Redolfi, J; et al. Interaction of Nup53 with Ndc1 and Nup155 is required for nuclear pore complex assembly. JOURNAL OF CELL SCIENCE 127:908-921(2014).
    • Vollmer, B; Schooley, A; et al. Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO JOURNAL 31:4072-4084(2012).

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