NUP153
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Official Full Name
NUP153 nucleoporin 153kDa -
Overview
The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. This hybridoma has been established by Prof. T. Tachibana’s Lab at Osaka City Univ. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes. -
Synonyms
NUP153;nucleoporin 153kDa;nucleoporin 153kD;nuclear pore complex protein Nup153;HNUP153;nucleoporin Nup153;153 kDa nucleoporin;nuclear pore complex protein hnup153;N153
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NUP153-1414H | Recombinant Human NUP153, GST-tagged | E.coli | Human | GST | 1125-1475aa | |
| NUP153-3136R | Recombinant Rhesus monkey NUP153 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| NUP153-2777H | Recombinant Human NUP153 protein(341-410 aa), C-His-tagged | E.coli | Human | His | 341-410 aa |
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| NUP153-2954R | Recombinant Rhesus Macaque NUP153 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| NUP153-2954R-B | Recombinant Rhesus Macaque NUP153 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| NUP153-5383H | Recombinant Human NUP153 Protein (Ser1238-Lys1468), N-GST tagged | E.coli | Human | GST | Ser1238-Lys1468 |
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| NUP153-695H | Recombinant Human NUP153 Protein (657-880 aa), His-tagged | E.coli | Human | His | 657-880 aa |
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Involved Pathway
NUP153 involved in several pathways and played different roles in them. We selected most pathways NUP153 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP153 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | SMN,NXT1,DDX39B,EIF2B3,NCBP1,THOC7,EIF3EA,UPF1,EIF3BA,XPO5 |
Protein Function
NUP153 has several biochemical functions, for example, DNA binding,Ran GTPase binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP153 itself. We selected most functions NUP153 had, and list some proteins which have the same functions with NUP153. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of nuclear pore | NUP54,NUP155,NUP107,NUP98,NUP62CL,TMEM33,NUP205,NUP62L,NUP93,NDC1 |
| transporter activity | ABCA6,SLC2A15A,SLC5A10,ABCA4,OCA2,SLC13A2,SLCO1F3,SYPL,TAP2,SYN1 |
| Ran GTPase binding | XPO6,IPO8,IPO5,IPO9,RANBP3,KPNB1,TNPO1,BIRC5,IPO4,RANGRF |
| DNA binding | PATZ1,GTF2IRD1,SIX6A,SMARCAD1,HER12,ANKRD1,RAD54B,NPAS4,TRIM26,ZFP488 |
| zinc ion binding | MT1G,NR2F2,CPA6,LMO4A,ZFYVE1,PDXK,ZDHHC16B,RNF144A,RNFT2,NANOS3 |
| nucleocytoplasmic transporter activity | RBM22,UPF3A,NUPL1,NUP214,NUP107,XPO1,TPR,TPRB,NUP54,NUP160 |
| protein binding | CATSPERG2,RIMS1,SORL1,IGHM,STARD3,PDP1,CKB,DPYSL2,KRTAP3-2,SF3A2 |
| protein anchor | CIB1,ALG14,MYH9,SUN5,SUN1,RAPSN,SLC4A1,SUN3,PDCD6,AKAP6 |
| identical protein binding | CBS,APPL1,EED,LRRK1,VWF,GBP1,YWHAZ,IK,CLDND,L1CAM |
Interacting Protein
NUP153 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP153 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP153.
NXF1;KPNB1;EPHB2;MAPK14;RAN;NUP133;gag-pol
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References
- Chang, CW; Lee, CP; et al. BGLF4 Kinase Modulates the Structure and Transport Preference of the Nuclear Pore Complex To Facilitate Nuclear Import of Epstein-Barr Virus Lytic Proteins. JOURNAL OF VIROLOGY 89:1703-1718(2015).
- Pante, N; Fahrenkrog, B; et al. Exploring Nuclear Pore Complex Molecular Architecture by lmmuno-Electron Microscopy Using Xenopus Oocytes. NUCLEAR PORE COMPLEXES AND NUCLEOCYTOPLASMIC TRANSPORT - METHODS 122:81-98(2014).
