NUDT5
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Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 5 -
Overview
Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of;important signaling nucleotides and their metabolites (McLennan, 1999 (PubMed 10373642)). -
Synonyms
NUDT5;nudix (nucleoside diphosphate linked moiety X)-type motif 5;ADP-sugar pyrophosphatase;hYSAH1;YSA1H;ADP sugar pyrophosphatase;hYSAH 1;Nucleoside diphosphate linked moiety X motif 5;Nucleoside diphosphate linked moiety X type motif 5;Nucleoside diphosphate-linked moiety X motif 5;Nudix (nucleoside diphosphate linked moiety X) type motif 5;Nudix motif 5;Nudix type motif 5;NUDT 5;NUDT5_HUMAN;YSA1;OTTHUMP00000019112;OTTHUMP00000019113;OTTHUMP00000019114;OTTHUMP00000019116;OTTHUMP00000019117;nucleoside diphosphate linked moiety X-type motif 5
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- Rat
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- GST
- Avi
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
NUDT5 involved in several pathways and played different roles in them. We selected most pathways NUDT5 participated on our site, such as Metabolism,Metabolism of nucleotides,Phosphate bond hydrolysis by NUDT proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phosphate bond hydrolysis by NUDT proteins | NUDT16,NUDT1,NUDT18,NUDT15 |
| Metabolism of nucleotides | AK7,NUDT1,DPYD,ADAL,TM9SF1,PNP5B,DPYS,ADSS,ADK,PAICS |
| Purine metabolism | PGM2,ADK,NT5C,NME2B.1,IMPDH1A,POLR3K,GDA,NT5M,NT5C3L,ADSL |
| Metabolism | NHLRC1,YY2,DECR1,ELA2,COX16,LRPPRC,CTH,AZIN1A,SIN3B,GLRX |
Protein Function
NUDT5 has several biochemical functions, for example, ADP-ribose diphosphatase activity,ADP-sugar diphosphatase activity,NOT m7G(5)pppN diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT5 itself. We selected most functions NUDT5 had, and list some proteins which have the same functions with NUDT5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| magnesium ion binding | PPM1NB,IDH1,IDH3B,TREX2,PGM2,ZNF143B,STK36,ADSS,ADPRH,NT5C1A |
| NOT m7G(5)pppN diphosphatase activity | NUDT4,NUDT7,NUDT16L1,NUDT1 |
| nucleoside-diphosphatase activity | ENTPD1,ENTPD8,ENTPD3 |
| ADP-ribose diphosphatase activity | ADPRM,TRPM2,NUDT14,NUDT9 |
| ADP-sugar diphosphatase activity | NUDT9 |
| snoRNA binding | NHP2,NUDT16,NOP14,HEATR1,PWP2H,NUDT16L1,NOP58,NUDT7,DDX21,WDR3 |
Interacting Protein
NUDT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT5.
Mad2l1;GH1;MCC;HLA-B;EIF6;IKBKE;FTSJ1;PRKAB1;TRAF6;MCM3AP;NUDT3;MAPK6;q8ckd5_yerpe;HSPB9;MAD2L1;IFI16;SKA1
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