NUCB1
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Official Full Name
nucleobindin 1 -
Overview
This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. -
Synonyms
NUCB1;nucleobindin 1;nucleobindin-1;Calnuc;NUC;FLJ40471;DKFZp686A15286
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- His&T7
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
NUCB1 involved in several pathways and played different roles in them. We selected most pathways NUCB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NUCB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
NUCB1 has several biochemical functions, for example, DNA binding,G-protein alpha-subunit binding,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUCB1 itself. We selected most functions NUCB1 had, and list some proteins which have the same functions with NUCB1. You can find most of the proteins on our site.
Function | Related Protein |
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DNA binding | ACD,FOXS1,ADNP,DDX41,POLR3H,ZNF34,KAT6B,ZNF18,ZFP92,ARID3C |
G-protein alpha-subunit binding | PPP5C,RGS14,IGF1R,CRHR1,LPAR3,F2RL1,DRD1,AGTR1A,HTR2A,OPRM1 |
protein binding | UBE3C,DCAF12L1,IQCE,PPP5C,ARL4A,ZBTB17,GABARAPL2,CENPP,FOXO3,BRAF |
calcium ion binding | HPGDS,TPM4,S100A4,RHOT1A,MASP2,PCDHB1,FBLN7,C2CD4B,OCM2,PLCG1 |
Interacting Protein
NUCB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUCB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUCB1.
q99ib8-pro_0000045603;CASP6;CASP8;XPO1;MYC;GNAI3;ul31_ebvb9;HIVEP1;RBL1;GNAI1;GNAS;SET;gM;q9wmx2-pro_0000037550;q9wmx2-pro_0000037551;HSPA5
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References
- Goebel-Stengel, M; Wang, LX; et al. Central and Peripheral Expression and Distribution of NUCB2/nesfatin-1. CURRENT PHARMACEUTICAL DESIGN 19:6935-6940(2013).
- Guo, FF; Xu, L; et al. The effects of nesfatin-1 in the paraventricular nucleus on gastric motility and its potential regulation by the lateral hypothalamic area in rats. JOURNAL OF NEUROCHEMISTRY 132:266-275(2015).