NSFL1C
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Official Full Name
NSFL1 (p97) cofactor (p47) -
Overview
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. -
Synonyms
NSFL1C;NSFL1 (p97) cofactor (p47);NSFL1 cofactor p47;dJ776F14.1;p47;SHP1 homolog (S. cerevisiae);UBX domain protein 2C;UBX1;UBXD10;UBXN2C;MGC3347;OTTHUMP00000029972;OTTHUMP00000029974;P47 protein;P97 cofactor p47;SHP1 homolog;UBX domain-containing protein 2C
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
Involved Pathway
NSFL1C involved in several pathways and played different roles in them. We selected most pathways NSFL1C participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with NSFL1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | HSP90AA1.2,MAPK8,PDIA4,ERP29,SSR3,UBE2D2,ATXN3,UBE2J1,HSPA1L,UBE2D3 |
Protein Function
NSFL1C has several biochemical functions, for example, ATPase binding,phospholipid binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NSFL1C itself. We selected most functions NSFL1C had, and list some proteins which have the same functions with NSFL1C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase binding | ATP6V0A2,DNAJB1,PTPN3,TCIRG1,SLN,TOR1AIP2,ATP6V0A1B,ATP6V0A1A,ZNHIT6,USP25 |
| protein phosphatase type 1 regulator activity | PPP1R15A,UBXN2A,PHACTR3A,UBXN2B,PPP1R16A,KCNS1,PHACTR4B,PPP1R16B,PHACTR1,PHACTR3 |
| ubiquitin binding | VPS36,UBXN2A,UBR5,FAF1,DNAJC2,KIF18A,TSG101,DYRK2,NEDD4,IWS1 |
| phospholipid binding | DAPP1,AGAP1,FABP1,SHC1,SPTBN2,GRK5,SEC14L2,LPAR3,OTC,PRKCI |
| protein binding | EDNRB,PPP1CC,GJB6,RMND1,TINAGL1,GAS7,FAM64A,GPRASP2,CARKD,ARHGAP17 |
Interacting Protein
NSFL1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NSFL1C here. Most of them are supplied by our site. Hope this information will be useful for your research of NSFL1C.
VCP;HEL-S-70;VCPIP1;DBI;RPL22;SRP14;ANP32A;GSK3B;LIPE;TARDBP;GLMN;PHAX;FAM32A;Insr
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