NSA2
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Official Full Name
NSA2 Ribosome Biogenesis Homolog (S. cerevisiae) -
Overview
Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. It is usually classified as a sub-type of chronic lymphoid leukemia. Hairy cell leukemia makes up approximately 2% of all leukemias, with fewer than 2,000 new cases diagnosed annually in North America and Western Europe combined.Hairy cell leukemia was originally described as histiocytic leukemia, malignant reticulosis, or lymphoid myelofibrosis in publications dating back to the 1920s. The disease was formally named leukemic reticuloendotheliosis and its characterization significantly advanced by Bertha Bouroncle and colleagues at The Ohio State University College of Medicine in 1958. Its common name, which was coined in 1966, is derived from the "hairy" appearance of the malignant B cells under a microscope. -
Synonyms
NSA2;NSA2 ribosome biogenesis homolog (S. cerevisiae);ribosome biogenesis protein NSA2 homolog;FLJ94393;hairy cell leukemia protein 1;HCLG1;HUSSY 29;TGF beta inducible nuclear protein 1;TINP1;OTTHUMP00000161947;TGF-beta inducible nuclear protein;TGF beta-inducible nuclear protein 1;TGF-beta-inducible nuclear protein 1;YR-29;CDK105;HCL-G1;HUSSY29;HUSSY-29
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Zebrafish
- Human
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NSA2-10906M | Recombinant Mouse NSA2 Protein | Mammalian Cell | Mouse | His |
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| NSA2-1716C | Recombinant Chicken NSA2 | Mammalian Cell | Chicken | His |
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| NSA2-3107R | Recombinant Rhesus monkey NSA2 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| NSA2-9971Z | Recombinant Zebrafish NSA2 | Mammalian Cell | Zebrafish | His |
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| NSA2-3689HCL | Recombinant Human NSA2 293 Cell Lysate | HEK293 | Human | Non |
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| NSA2-2926R | Recombinant Rhesus Macaque NSA2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| NSA2-2926R-B | Recombinant Rhesus Macaque NSA2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| NSA2-6217M | Recombinant Mouse NSA2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NSA2-6217M-B | Recombinant Mouse NSA2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NSA2 involved in several pathways and played different roles in them. We selected most pathways NSA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NSA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NSA2 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NSA2 itself. We selected most functions NSA2 had, and list some proteins which have the same functions with NSA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | COA6,STAU2,C3orf26,RPS12,MSI1,SNW1,DUSP14,ZFP579,RPS28,DIAP1 |
Interacting Protein
NSA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NSA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NSA2.
iucD;IRAK3;MNDA;IFI16;CAMKK1
Resources
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References
- Bassler, J; Paternoga, H; et al. A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. JOURNAL OF CELL BIOLOGY 207:481-498(2014).
- Shahni, R; Czajka, A; et al. Nop-7-associated 2 (NSA2), a candidate gene for diabetic nephropathy, is involved in the TGF beta 1 pathway. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 45:626-635(2013).
