NRIP1

  • Official Full Name

    nuclear receptor interacting protein 1

  • Overview

    Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]

  • Synonyms

    NRIP1;nuclear receptor interacting protein 1;RIP140;nuclear receptor-interacting protein 1;nuclear factor RIP140;receptor interacting protein 140;receptor-interacting protein 140
Cat.# Product name Source (Host) Species Tag Protein Length Price
NRIP1-10890M Recombinant Mouse NRIP1 Protein Mammalian Cell Mouse His
NRIP1-3695HCL Recombinant Human NRIP1 293 Cell Lysate HEK293 Human Non
NRIP1-6202M Recombinant Mouse NRIP1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NRIP1-6202M-B Recombinant Mouse NRIP1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NRIP1 involved in several pathways and played different roles in them. We selected most pathways NRIP1 participated on our site, such as Adipogenesis,BMAL1:CLOCK,NPAS2 activates circadian gene expression,Circadian Clock, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adipogenesis STIL,E2F1,BSCL2,EGR2B,RORAA,CFD,CYP26A1,E2F4,EBF1,AHR
    Circadian Clock CRY1,HELZ2,NAMPT,DBP,CRY2,RAI1,CPT1A,CSNK1E,CARM1
    FOXA1 transcription factor network NFIB,POU2F1,NFIA,FOXA1,NR2F2,CYP2C18,TFF1,CEBPB,CC10,AP1B1
    Coregulation of Androgen receptor activity PAWR,SVIL,SNURF,TCF4,TGFB1I1,ZMIZ1,PIAS3,PA2G4,KDM3A,CTDSP1
    Retinoic acid receptors-mediated signaling RBP1
    Ovarian Infertility Genes SYNE2,INHA,NR5A1,DMC1,GJA4,ZP3,DAZL,MSH5,ZP2
    BMAL1:CLOCK,NPAS2 activates circadian gene expression NAMPT,CRY2,CREBBP,NCOA2,CRY1,DBP,HELZ2,CARM1

    Protein Function

    NRIP1 has several biochemical functions, for example, androgen receptor binding,core promoter sequence-specific DNA binding,estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRIP1 itself. We selected most functions NRIP1 had, and list some proteins which have the same functions with NRIP1. You can find most of the proteins on our site.

    Function Related Protein
    retinoid X receptor binding NSD1,HMGA1-RS1,NR0B2,RARB,NCOA1,MED25,NR4A2,FUS,NR1H4,HMGA1
    transcription corepressor activity KCTD1,ATF3,CITED2,CTCF,HEYL,SRSF2,SAP18,HDAC4,ZNF274,SP100
    core promoter sequence-specific DNA binding SOHLH2,NR4A3,THRAP3,MEOX1,ZFHX3,NR1D2,ZFP750,ESR2,C1orf51,TP53
    protein binding C22orf23,CT45A3,ZNF550,SENP6,ARL2,C1orf21,PLEK,HIRIP3,RPL23A,MRPL44
    glucocorticoid receptor binding FKBP4,EP300,ETS2,GRIP1,NR4A2,STAT5B,YWHAH,STAT3,CEBPB
    androgen receptor binding RB1,Ar,PRPF6,KDM3A,GRIP1,TGFB1I1,KAT5,DDX5,BRCA1,KDM1A
    histone deacetylase binding KLF4,BRMS1LA,XBP1,CRY1,RAD9,SUDS3,PRDM1,ZNF703,MEF2B,MECP2
    estrogen receptor binding CCDC62,ISL1,NKX3-1,DDX17,HSD17B10,NSD1,PCNA,MMS19,TMEM38A,CNOT1
    nuclear hormone receptor binding EP300,CTNNB1,ACTN4,NCOA3,CRY1,CRX,HIF1A,MYOD1,BUD31,MED1

    Interacting Protein

    NRIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRIP1.

    RARA;FHL1;LDOC1;CEP70;PRMT1

    Resources

    References

    • Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
    • Pisetsky, DS; et al. The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE. AUTOIMMUNITY 47:487-493(2014).

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