NPFFR2

  • Official Full Name

    neuropeptide FF receptor 2

  • Overview

    This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants.

  • Synonyms

    NPFFR2;neuropeptide FF receptor 2;G protein coupled receptor 74 , GPR74;neuropeptide FF 2;NPFF2;NPGPR;G protein coupled receptor 74;G protein coupled receptor HLWAR 77;G protein coupled receptor HLWAR77;G-protein coupled receptor 74;G-protein coupled receptor HLWAR77;GPR 74;GPR74;HLWAR 77;HLWAR77;Neuropeptide G protein coupled receptor;Neuropeptide G-protein coupled receptor;NPFF 2;NPFF R2;NPFF2_HUMAN;NPFFR 2;G protein-coupled receptor 74

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Rat
  • Mus musculus
  • E.coli
  • Mammalian Cell
  • HEK293
  • Yeast
  • Wheat Germ
  • In Vitro Cell Free System
  • E.coli expression system
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NPFFR2-1341H Recombinant Human NPFFR2, His-tagged E.coli Human His 346-420aa
NPFFR2-10818M Recombinant Mouse NPFFR2 Protein Mammalian Cell Mouse His
NPFFR2-3283C Recombinant Chicken NPFFR2 Mammalian Cell Chicken His
NPFFR2-4041R Recombinant Rat NPFFR2 Protein Mammalian Cell Rat His
NPFFR2-1209HCL Recombinant Human NPFFR2 cell lysate Human Non
NPFFR2-3700R Recombinant Rat NPFFR2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
NPFFR2-3700R-B Recombinant Rat NPFFR2 Protein Pre-coupled Magnetic Beads HEK293 Rat
NPFFR2-5486H Recombinant Human NPFFR2 protein, His-tagged Yeast Human His 1-420aa
NPFFR2-6025H Recombinant Human NPFFR2 Protein Wheat Germ Human Non
NPFFR2-6157M Recombinant Mouse NPFFR2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NPFFR2-6157M-B Recombinant Mouse NPFFR2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
NPFFR2-6618HF Recombinant Full Length Human NPFFR2 Protein In Vitro Cell Free System Human Full L. 187 amino acids
RFL1175HF Recombinant Full Length Human Neuropeptide Ff Receptor 2(Npffr2) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-522)
RFL20677MF Recombinant Full Length Mouse Neuropeptide Ff Receptor 2(Npffr2) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-417)
RFL23439RF Recombinant Full Length Rat Neuropeptide Ff Receptor 2(Npffr2) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-417)

    Involved Pathway

    NPFFR2 involved in several pathways and played different roles in them. We selected most pathways NPFFR2 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPFFR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gastrin-CREB signalling pathway via PKC and MAPK DGKG,NTS,TRH,PRKCHB,GPR132,DGKQ,RGS18,UTS2,ANXA1C,OPN4A
    Neuroactive ligand-receptor interaction TAAR10D,PTGER2,SSTR4,GRM8B,GRM5,GABRG1,CSH1,GRM7,SSTR1,FSHR
    G alpha (q) signalling events KISS1,GPR132B,DGKB,GPR17,GPR132,FFAR3,FPR-RS3,CYSLTR1,ANXA1C,GPR4
    GPCRs, Class A Rhodopsin-like GPR18,FPR-RS4,GPR68,PTGDR2,ACKR4,APLNR,FPR-RS3,GPR20,OPN1LW,GPR6
    Class A/1 (Rhodopsin-like receptors) GPR132B,CGA,GPR4,AGTR1,GAL,GPR31B,OXER1,OPN1MW2,CCK,APLNR
    GPCR downstream signaling HEBP1,ADORA2B,ADM,GCGA,ANXA1B,ANXA1,OPN1MW2,CGA,CCL35.2,APLN
    Orexin and neuropeptides FF and QRFP bind to their respective receptors QRFPR,HCRT,NPFF,QRFP
    GPCR ligand binding PROKR1A,TRH,SSTR3,GPR55A,DRD4,CXCR6,EDNRB,NMB,HCRT,KEL

    Protein Function

    NPFFR2 has several biochemical functions, for example, G-protein coupled receptor activity,neuropeptide receptor activity,opioid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NPFFR2 itself. We selected most functions NPFFR2 had, and list some proteins which have the same functions with NPFFR2. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity TAS2R106,HTR1AA,GHSRA,OLFR998,OR51D1,OLFCG3,GPR124,GHRHR2,GNRHR3,KISS1RB
    peptide binding CTSL2,CRHBP,PLOD1,Npepo,TPP1,NLN,FURIN,NPFFR1L3,CMA1,ANPEP
    neuropeptide receptor activity NPFFR1L3,PRLHR,NPFFR2.1,KISS1RA,HCRTR2,HCRTR1,NPBWR2,NPFFR1,SORCS2,KISS1R
    opioid receptor binding NPFFR2.1

    Interacting Protein

    NPFFR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPFFR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPFFR2.

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All NPFFR2 Products

    Required fields are marked with *

    My Review for All NPFFR2 Products

    Required fields are marked with *