NOVA1
-
Official Full Name
neuro-oncological ventral antigen 1 -
Overview
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. -
Synonyms
NOVA1;neuro-oncological ventral antigen 1;RNA-binding protein Nova-1;ventral neuron-specific protein 1;Nova-1;G630039L02;9430099M15Rik
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Zebrafish
- Chicken
- Cynomolgus
- Mammalian Cell
- Wheat Germ
- E. coli
- HEK293
- In Vitro Cell Free System
- HEK293T
- E.coli
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
- Flag
Involved Pathway
NOVA1 involved in several pathways and played different roles in them. We selected most pathways NOVA1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NOVA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NOVA1 has several biochemical functions, for example, RNA binding,mRNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOVA1 itself. We selected most functions NOVA1 had, and list some proteins which have the same functions with NOVA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | EXOSC3,SETD1BA,PRDM14,PSMA1,KHDC1C,ENDOU,FAM120A,PUS3,ADARB1A,NR0B1 |
| poly(A) RNA binding | TRIM56,MRPS28,CROP,ZFP326,RBMX,EDF1,FAM120A,ZAK,MYH9,NAT10 |
| mRNA binding | CLUHA,NUDT21,DCP1B,FXR1,KIAA0020,CROP,ESRP1,AGO2,SRSF1,TRA2B |
Interacting Protein
NOVA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOVA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NOVA1.
SRPK1;RPP14;PCBP1;SMARCC2
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