NOTCH1A
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Official Full Name
notch homolog 1a -
Synonyms
NOTCH1A;notch homolog 1a;neurogenic locus notch homolog protein 1;Deadly seven;des;n1a;Notch 1a;wu:fc01e02;wu:fc37a05
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NOTCH1A-9009Z | Recombinant Zebrafish NOTCH1A | Mammalian Cell | Zebrafish | His |
|
Involved Pathway
NOTCH1A involved in several pathways and played different roles in them. We selected most pathways NOTCH1A participated on our site, such as Dorso-ventral axis formation,Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NOTCH1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Notch signaling pathway | NOTCH3,HES1,DLL3,CTBP1,HDAC1,RBPJ,HER15.1,KAT2A,DLK1,TLE3A |
| Dorso-ventral axis formation | SPIRE1,NOTCH1B,PPP1R2P9,PIWIL4,CPEB1A,NOTCH4,EGFRA,GRB2,SPIRE2,CPEB1B |
Protein Function
NOTCH1A has several biochemical functions, for example, calcium ion binding,metal ion binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NOTCH1A itself. We selected most functions NOTCH1A had, and list some proteins which have the same functions with NOTCH1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | MICALL2B,RXRAA,NEURL1B,SHHA,ZNF274,ZNF41,SAR1B,IDO2,TRIM2A,MAP3K2 |
| receptor activity | KRT1,P2RY2,NPC1,KIR2DL1,RAMP1,VMN1R40,ITGB8,SV2A,VMN1R49,LILRB2 |
| calcium ion binding | DLL4,NOTCH4,PVALB5,PCDHGB6,REPS1,PLSCR4,BNIP2,EMR3,CALUA,ANXA1A |
Interacting Protein
NOTCH1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOTCH1A here. Most of them are supplied by our site. Hope this information will be useful for your research of NOTCH1A.
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References
- Li, IC; Chan, CT; et al. Zebrafish Kruppel-Like Factor 4a Represses Intestinal Cell Proliferation and Promotes Differentiation of Intestinal Cell Lineages. PLOS ONE 6:-(2011).
- Franberg, J; Svensson, AI; et al. Minor contribution of presenilin 2 for gamma -secretase activity in mouse embryonic fibroblasts and adult mouse brain. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 404:564-568(2011).
