NLRP6
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Official Full Name
NLR family, pyrin domain containing 6 -
Overview
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs,;such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a;NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636),;also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD).;NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in;multiprotein complexes called inflammasomes (Tschopp et al., 2003 (PubMed 12563287)). -
Synonyms
NLRP6;NLR family, pyrin domain containing 6;NACHT, LRR and PYD domains-containing protein 6;CLR11.4;NACHT, leucine rich repeat and PYD containing 6;NACHT, LRR and PYD containing protein 6;NALP6_HUMAN;Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6;PAN3;PYPAF5;PYRIN containing APAF1 like protein 5;PYRIN-containing APAF1-like protein 5;angiotensin;angiotensin II/vasopressin receptor;dual angiotensin II/vasopressin receptor;Nalp6
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mammalian Cells
- Insect Cells
- HEK293
- Insect cells
- His
- Non
- MBP&His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NLRP6-3049R | Recombinant Rhesus monkey NLRP6 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| NLRP6-4000R | Recombinant Rat NLRP6 Protein | Mammalian Cells | Rat | His |
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| NLRP6-0069H | Recombinant Human NLRP6 Protein (M1-F892), Tag Free | Insect Cells | Human | Non | M1-F892 |
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| NLRP6-0070H | Recombinant Human NLRP6 Protein (M1-F892), His/MBP tagged | Insect Cells | Human | MBP&His | M1-F892 |
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| NLRP6-2868R | Recombinant Rhesus Macaque NLRP6 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| NLRP6-2868R-B | Recombinant Rhesus Macaque NLRP6 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| NLRP6-3659R | Recombinant Rat NLRP6 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| NLRP6-3659R-B | Recombinant Rat NLRP6 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| NLRP6-6453H | Recombinant Human NLRP6 protein, His-tagged | Insect cells | Human | His | 1-892aa |
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Involved Pathway
NLRP6 involved in several pathways and played different roles in them. We selected most pathways NLRP6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NLRP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NLRP6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NLRP6 itself. We selected most functions NLRP6 had, and list some proteins which have the same functions with NLRP6. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
NLRP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLRP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLRP6.
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