NLGN3
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Official Full Name
neuroligin 3 -
Overview
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
NLGN3;neuroligin 3;neuroligin-3;ASPGX1;AUTSX1;HNL3;KIAA1480;Gliotactin homolog;OTTHUMP00000023498;OTTHUMP00000023499;OTTHUMP00000023500
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- HEK293
- Mammalian Cells
- Human Cells
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- Non
- Flag
- His&Fc&Avi
- GST
Involved Pathway
NLGN3 involved in several pathways and played different roles in them. We selected most pathways NLGN3 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with NLGN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | CLDNG,ALCAM,CLDN18,ICAM1,CD99,JAM2A,HLA-DPA1,PRPSAP2,PVRL1B,CLDNH |
Protein Function
NLGN3 has several biochemical functions, for example, cell adhesion molecule binding,NOT cholinesterase activity,neurexin family protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NLGN3 itself. We selected most functions NLGN3 had, and list some proteins which have the same functions with NLGN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | PVRL1A,THBD,GABRA5,EXTL3,CD244,EDAR,SLC40A1,ANTXRL,TLR4,TREM1 |
| protein binding | LGALS13,ZNF473,TIMM44,LRP5,MEN1,ZNF83,RAB24,PASK,MYBPHL,PTPRN |
| scaffold protein binding | TREM2,KRT8,NOS3,SRC,KCNA5,VIM,CASP8,KCNQ1,GRIN2A,NOS1 |
| cell adhesion molecule binding | TENM2,SMAGP,NCR3,PVRL3B,Fert2,POSTN,AMICA1,ADAM8,ITGB3,DSG2 |
| neurexin family protein binding | SYTL2,CPE,CASK,NLGN4B,NLGN2B,NLGN3A,NLGN2A,SDCBP,NLGN2,SYTL1 |
| NOT cholinesterase activity | NLGN3B,NLGN3A,NLGN2B,NLGN1,NLGN2A,NLGN2,NLGN4X,NLGN4Y,NLGN4A,NLGN4B |
Interacting Protein
NLGN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLGN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLGN3.
TGFBR1;PRDX2
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