NKX2-8
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Official Full Name
NK2 homeobox 8 -
Synonyms
NKX2-8;NK2 homeobox 8;NK 2 homolog H (Drosophila) , NK2 transcription factor related, locus 8 (Drosophila) , NKX2H;homeobox protein Nkx-2.8;Nkx2 9;NKX2.8;Homeobox protein NK 2 homolog H;Homeobox protein NK-2 homolog H;Homeobox protein Nkx 2.8;NK 2 homolog 8;NK 2 homolog H;NK2 transcription factor related, locus 8;NKX28_HUMAN;NKX2G;NKX2H;OTTHUMP00000027959;NK-2 homolog 8;NK-2 homolog H;Nkx2-9
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NKX2-8-1304H | Recombinant Human NKX2-8, GST-tagged | E.coli | Human | GST | 1-160aa | |
| NKX2-8-2497H | Recombinant Human NKX2-8 protein, His-tagged | E.coli | Human | His | 1-160 aa | |
| NKX2-8-1199HCL | Recombinant Human NKX2-8 cell lysate | Human | Non |
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| NKX2-8-5901H | Recombinant Human NKX2-8 Protein, GST-tagged | Wheat Germ | Human | GST | 1-239 a.a. |
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| NKX2-8-6704HF | Recombinant Full Length Human NKX2-8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 239 amino acids |
|
Involved Pathway
NKX2-8 involved in several pathways and played different roles in them. We selected most pathways NKX2-8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX2-8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NKX2-8 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,double-stranded DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX2-8 itself. We selected most functions NKX2-8 had, and list some proteins which have the same functions with NKX2-8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | KLF13,ATOH1,TCF21,ELF3,MAFA,MAFB,NFIB,POU4F2,MTF1,TP63 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | MYBL1,POU3F2,GATA4,MYOD1,NEUROD6,ZNF253,DDN,GATA1,TCF3A,NR2C1 |
| transcription factor activity, sequence-specific DNA binding | ZNF445,ZFP821,DDIT3,FOXO4,PCGF2,MAX,ZNF454,BLZF1,ETV5B,IRF9 |
| sequence-specific DNA binding | MAEL,NANOGP8,CALCOCO1,NFE2L1B,SFPI1,RAG1,ZFP13,MIXL1,RORB,GSC |
| double-stranded DNA binding | RAD51L3,NTHL1,SETMAR,RBMS1,RAD51,XRCC5,HMGB3,USF1,RAD51D,MCM10 |
Interacting Protein
NKX2-8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX2-8 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX2-8.
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References
- Pereda, CM; Lesueur, F; et al. Common variants at the 9q22.33, 14q13.3 and ATM loci, and risk of differentiated thyroid cancer in the Cuban population. BMC GENETICS 16:-(2015).
- Fennell, DA; Myrand, SP; et al. Association between Gene Expression Profiles and Clinical Outcome of Pemetrexed-Based Treatment in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer: Exploratory Results from a Phase II Study. PLOS ONE 9:-(2014).
