NKD1
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Official Full Name
naked cuticle homolog 1 (Drosophila) -
Overview
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway. -
Synonyms
NKD1;naked cuticle homolog 1 (Drosophila);protein naked cuticle homolog 1;Dvl-binding protein;naked cuticle 1 homolog;Naked-1;NKD;naked cuticle-1;Naked1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NKD1-3851Z | Recombinant Zebrafish NKD1 | Mammalian Cells | Zebrafish | His |
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| NKD1-860H | Recombinant Human NKD1 | Mammalian Cells | Human | His |
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| NKD1-3627H | Recombinant Human NKD1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| NKD1-3627H-B | Recombinant Human NKD1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
NKD1 involved in several pathways and played different roles in them. We selected most pathways NKD1 participated on our site, such as Wnt signaling pathway,Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NKD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hippo signaling pathway | GLI2,WNT6,STK3,WNT8B,PARD3,SMAD3,DVL3,FGF1,FZD8,BMP7 |
| Wnt signaling pathway | TP53,WNT7B,DVL1B,WNT2B,PRKACBB,PPP3CCB,INVS,SFRP1,VANGL1,WNT2 |
Protein Function
NKD1 has several biochemical functions, for example, PDZ domain binding,calcium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKD1 itself. We selected most functions NKD1 had, and list some proteins which have the same functions with NKD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | DLG3,SLC22A5,GRID2,LPAR2,GRM7,F11R,NSF,ADRB1,NLGN1,ATP2B1A |
| calcium ion binding | NOL3,DSG1,SPOCK3,S100A8,CDH11,CAPSL,NELL2A,CAPN3B,SULF2A,ADAMTS13 |
| protein binding | FAM9C,EPHB1,EFHC1,NRIP1,HHIPL2,SORL1,CACNA1SB,PLEKHG4,SLX4,SMAD9 |
Interacting Protein
NKD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKD1.
PPP2R3A;PPP2R3A;PPP2R1A;PPP2CA;Dvl1
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