NFX1
-
Official Full Name
nuclear transcription factor, X-box binding 1 -
Overview
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. -
Synonyms
NFX1;nuclear transcription factor, X-box binding 1;transcriptional repressor NF-X1;MGC20369;NFX2;NFX 1;Nuclear transcription factor X box binding 1;Nuclear transcription factor X box binding protein 1;Transcriptional repressor NF X1;OTTHUMP00000021213;OTTHUMP00000021214;OTTHUMP00000021215;nuclear transcription factor, X box-binding protein 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NFX1-1284H | Recombinant Human NFX1, His-tagged | E.coli | Human | His | 771-1120aa | |
| NFX1-3842HCL | Recombinant Human NFX1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Nfx1-1824M | Recombinant Mouse Nfx1 Protein, His-tagged | E.coli | Mouse | His | His859-Asp1114 |
|
Involved Pathway
NFX1 involved in several pathways and played different roles in them. We selected most pathways NFX1 participated on our site, such as Binding and Uptake of Ligands by Scavenger Receptors,Scavenging of heme from plasma,Vesicle-mediated transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Binding and Uptake of Ligands by Scavenger Receptors | IGKC,APOA1B,HPX,Alb,SAA1,LOC479668,IGKV1-5,SCGB3A2,APOBB.1,COL1A2 |
| Scavenging of heme from plasma | LOC479668,AMBP,HP,HPX,CD163 |
| Vesicle-mediated transport | GJB5,TBC1D8B,AMBP,CLVS1,SH3D19,GAK,CTAGE5,AP3S1,CX30.3,COPB1 |
Protein Function
NFX1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NFX1 itself. We selected most functions NFX1 had, and list some proteins which have the same functions with NFX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
NFX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFX1.
UBE2N;UBE2D2;FAM46A
Resources
Related Services
Related Products
References
