NFIA
-
Official Full Name
nuclear factor I/A -
Overview
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] -
Synonyms
NFIA;nuclear factor I/A;CTF;NF1-A;NFI-A;NFI-L;NF-I/A;nuclear factor 1 A-type;TGGCA-binding protein;CCAAT-box-binding transcription factor
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
NFIA involved in several pathways and played different roles in them. We selected most pathways NFIA participated on our site, such as FOXA1 transcription factor network,Gene Expression,RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFIA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA Polymerase III Abortive And Retractive Initiation | POU2F1,SNAPC4,GTF3C5,ZNF143,SNAPC1,CRCP,BRF2,GTF3C2,NFIC,GTF3C4 |
| RNA Polymerase III Transcription Termination | NFIC,NFIX,NFIB |
| FOXA1 transcription factor network | NFIC,CC10,FOXA1,NRIP1,CYP2C18,NR2F2,NFIB,DSCAM,TFF1,POU2F1 |
| RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription | SNAPC1,MTA3,GATAD2B,CHD4A,GTF3AB,BRF2,NFIB,MBD3,RRN3,CRCP |
| RNA Polymerase III Transcription | GTF3A,ZNF143,BRF1,GTF3C3,NFIX,BRF1B,ZNF143B,GTF3C2,ZFP143,BRF2 |
| Gene Expression | NR2F6A,SNAPC3,ZNF311,DCP1B,TEAD1A,SF3B4,EEF1A1,ZNF559,ZNF180,HNRNPL |
Protein Function
NFIA has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,chromatin binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFIA itself. We selected most functions NFIA had, and list some proteins which have the same functions with NFIA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | ZKSCAN14,SIX3,IRF1B,ZNF263,ZNF571,ZFP37,SUPT6H,VAV1,ZNF92,PLAG1 |
| chromatin binding | RAD51,RNF2,ATXN7,MITF,MEIS3,TRIM37,HMGA1,GLI1,NR5A1,NCOA2 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | SMAD4,ZNF664,PAX8,ELK1,SRF,MYC,RUNX2,RFX8,BCL11A,RBPJ |
| transcription factor binding | HES1,GNPTAB,ZBTB49,HMGA1,EP300,FOXA1,Trl,POU1F1,LMO4,MED12L |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TFAP4,BSX,KLF15,NKX2-5,ETV2,SOX11,TFAP2A,MZF1,TFAP2C,EGR1 |
Interacting Protein
NFIA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFIA here. Most of them are supplied by our site. Hope this information will be useful for your research of NFIA.
dnb2_ade02;mdm2_human_probe
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