NDUFS7

  • Official Full Name

    NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

  • Overview

    This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain.;This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone;oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone;is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to;mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic;lesions in subcortical brain regions.

  • Synonyms

    NDUFS7;NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase);NADH dehydrogenase (ubiquinone) Fe S protein 7 (20kD) (NADH coenzyme Q reductase);CI 20;complex I 20kDa subunit;FLJ45860;FLJ46880;NADH dehydrogenase [ubiquinon

Recombinant Proteins

  • Mouse
  • Human
  • Zebrafish
  • Mammalian Cell
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NDUFS7-10547M Recombinant Mouse NDUFS7 Protein Mammalian Cell Mouse His
NDUFS7-562H Recombinant Human NDUFS7 Mammalian Cell Human His
NDUFS7-7890Z Recombinant Zebrafish NDUFS7 Mammalian Cell Zebrafish His
NDUFS7-3893HCL Recombinant Human NDUFS7 293 Cell Lysate HEK293 Human Non
NDUFS7-3607H Recombinant Human NDUFS7 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
NDUFS7-3607H-B Recombinant Human NDUFS7 Protein Pre-coupled Magnetic Beads HEK293 Human
NDUFS7-5993M Recombinant Mouse NDUFS7 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NDUFS7-5993M-B Recombinant Mouse NDUFS7 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NDUFS7 involved in several pathways and played different roles in them. We selected most pathways NDUFS7 participated on our site, such as Alzheimers disease,Electron Transport Chain,Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFS7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Parkinsons disease COX5A,ATP5G3,PRKACG,GNAL,UBA7,UBE2J2,NDUFS3,ATP5O,NDUFB2,COX7B
    Non-alcoholic fatty liver disease (NAFLD) COX7A2,UQCRC2,Casp3,PPARA,NDUFA4,NDUFC2-KCTD14,RELA,PKLR,INS,SDHB
    Alzheimers disease PPP3CC,MAPT,CAPN1,GRIN2C,CDK5,APAF1,NDUFA2,ATP5G3,UQCR11,COX5A
    Metabolism LBR,ABCA1,DUT,SLC25A21,GCHFR,SLC44A5B,CTGF,ARSJ,NFYBB,FA2H
    Metabolic pathways ACSL1B,ALDH18A1,CRLS1,PRPS1A,GAL3ST1A,MAN2A2,SLC33A1,LAP3,TPI1,RRM2
    Oxidative phosphorylation NDUFS8A,ATP5G3,SDHB,MT-ND4,ATP6V1C1B,SDHD,ATP4B,ATP5S,NDUFAB1A,COX4I2
    Huntingtons disease VDAC3,NDUFS6,NDUFS1,CREB3L1,UQCRC2,NDUFB11,APAF1,CREB3L2,TFAM,NDUFA10
    Electron Transport Chain ATP5L,UCP2,NDUFC2-KCTD14,COX6B1,COX7C,COX11,SLC25A27,COX4I1,SCO1,ATPIF1

    Protein Function

    NDUFS7 has several biochemical functions, for example, 4 iron, 4 sulfur cluster binding,NADH dehydrogenase (ubiquinone) activity,contributes_to NADH dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFS7 itself. We selected most functions NDUFS7 had, and list some proteins which have the same functions with NDUFS7. You can find most of the proteins on our site.

    Function Related Protein
    4 iron, 4 sulfur cluster binding NDUFS2,DPYDB,NTHL1,ISCA1,MUTYH,RSAD1,RSAD2,NUBPL,LIAS,DNA2
    NADH dehydrogenase (ubiquinone) activity NDUFA12,NDUFB5,NDUFA13,NDUFA3,NDUFA4,NDUFA1,NDUFC2-KCTD14,NDUFA8,NDUFB4,NDUFB6
    protein binding PDLIM7,CTDSP2,THRAP3,KDR,JAM3,GRIN2A,SULT4A1,MLLT1,TMEM93,TUBGCP2
    metal ion binding ZEB2A,NUDT13,RASA4,LNX2,MAP3K2,SP8,CHEK2,SOD3A,SMYD2B,ALOX5B.2
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor CBR1,DCXR,AKR1C21,AKR1C6,AKR1C3,AKR1C2,AKR1C4,DHRS4
    protease binding SERPINA5,CST3,CNTNAP2,IL1R1,TIMP2A,TRIP4,PEO1,SERPINA1D,SERPINA1E,FN1
    contributes_to NADH dehydrogenase activity NDUFV1,NDUFS8,NDUFS2
    quinone binding SQRDL,ABP1,NDUFS2,HHIPL1,AOC2,AOC1,AOC3,HHIPL2,VKORC1L1,CBR4

    Interacting Protein

    NDUFS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFS7.

    NDUFA2;ENO2;ARRB2;NDUFS8;NDUFS5;NDUFS2;NDUFS3;SCO1;ETHE1;NQO1;NDUFS1;LONP1;NDUFA6;ALDH6A1;NDUFA5;NDUFA9;NDUFAF5

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All NDUFS7 Products

    Required fields are marked with *

    My Review for All NDUFS7 Products

    Required fields are marked with *