NDUFB8
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -
Overview
NADH dehydrogenase1 beta subcomplex subunit 8, mitochondrial is an enzyme that in humans is encoded by the NDUFB8 gene. -
Synonyms
NDUFB8;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI);NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial;ASHI;CI ASHI;complex I ASHI subunit;mitochondrial;CI-ASHI;Complex I-ASHI;MS105;NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8 19kDa;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 mitochondrial;NADH-ubiquinone oxidoreductase ASHI subunit;NDUB8_HUMAN;NADH:ubiquinone oxidoreductase ASHI subunit
Recombinant Proteins
- Mouse
- Zebrafish
- Chicken
- Rhesus macaque
- Human
- Pan troglodytes
- Gorilla gorilla gorilla (Western lowland gorilla)
- Pongo Pygmaeus
- Pongo Abelii
- Mus musculus
- Mammalian Cell
- HEK293
- E.coli expression system
- His
- Non
- His&Fc&Avi
Involved Pathway
NDUFB8 involved in several pathways and played different roles in them. We selected most pathways NDUFB8 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFB8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CDO1,XDH,DHCR7,AMY2B,LPIN3,PSPH,PIP5K1BA,GKUP,EXT2,ACLYA |
| Huntingtons disease | Casp3,ATP5J,ITPR1,NDUFS4,COX7A1,COX7C,SDHC,NDUFB10,DNALC1,POLR2L |
| Non-alcoholic fatty liver disease (NAFLD) | BID,NDUFB11,NDUFB9,TGFB1,PIK3CB,NDUFB6,XBP1,NDUFS2,PIK3R2,IL6 |
| Parkinsons disease | COX7B,DRD1A,GPR37,PPIF,NDUFB10,SLC25A4,VDAC2,NDUFA1,NDUFB11,mt-Atp8 |
| Alzheimers disease | NDUFS2,UQCR10,CYCS,NDUFB9,FADD,ATP5J,LRP1,CDK5R1,CAPN1,COX7A1 |
| Oxidative phosphorylation | ATP6V1G1,NDUFS8B,ATP6V1E2,ATP6V1E1B,UQCRQ,COX6B2,ATP6V1G2,ATP6V1G3,SDHDB,ATP6V0D2 |
Protein Function
NDUFB8 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFB8 itself. We selected most functions NDUFB8 had, and list some proteins which have the same functions with NDUFB8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NADH dehydrogenase (ubiquinone) activity | NDUFAB1,NDUFB5,NDUFB1,NDUFB6,NDUFA1,NDUFA2,NDUFS2,NDUFV2,NDUFC2-KCTD14,NDUFS3 |
Interacting Protein
NDUFB8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFB8 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFB8.
NDUFA2;CACNA1A;PFN2;ZAP70;ATP6V0D2;EIF2B3;PIM2;2_aha_camp;NDUFS4;NDUFS5;NDUFS3;COX6C;RAB7A;NDUFA6;NDUFA9;Rmdn3;NDUFA11;TIMM21
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References
- Casal, A; Veyga, M; et al. Visceral organ mass, cellularity indexes and expression of genes encoding for mitochondrial respiratory chain proteins in pure and crossbred mature beef cows grazing different forage allowances of native pastures. LIVESTOCK SCIENCE 167:195-205(2014).
- Parnis, J; Chabosseau, PL; et al. The electron transport chain component NDUFB8 is required for glucose-stimulated insulin secretion in MIN6 cells. ACTA PHYSIOLOGICA 211:131-131(2014).
