NDOR1
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Official Full Name
NADPH dependent diflavin oxidoreductase 1 -
Overview
This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein is an enzyme that catalyzes the transfers electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants. -
Synonyms
NDOR1;NADPH dependent diflavin oxidoreductase 1;NADPH-dependent diflavin oxidoreductase 1;bA350O14.9;NADPH dependent FMN and FAD containing oxidoreductase;NR1;MGC138148;NADPH-dependent FMN and FAD-containing oxidoreductase;NDOR 1;NDOR1_HUMAN;Novel reductase 1;NR 1;OTTHUMP00000064742;RP11 350O14.11;OTTHUMP00000022695;OTTHUMP00000162579;NADPH-dependent FMN and FAD containing oxidoreductase;NADPH-dependent FMN and FAD-containing oxidoreduc
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NDOR1-1220H | Recombinant Human NDOR1, GST-tagged | E.coli | Human | GST | C-term-350aa | |
| NDOR1-10501M | Recombinant Mouse NDOR1 Protein | Mammalian Cell | Mouse | His |
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| NDOR1-10919Z | Recombinant Zebrafish NDOR1 | Mammalian Cell | Zebrafish | His |
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| NDOR1-3933HCL | Recombinant Human NDOR1 293 Cell Lysate | HEK293 | Human | Non |
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| NDOR1-1856H | Recombinant Human NDOR1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Ndor1-4323M | Recombinant Mouse Ndor1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| NDOR1-5956M | Recombinant Mouse NDOR1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NDOR1-5956M-B | Recombinant Mouse NDOR1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NDOR1 involved in several pathways and played different roles in them. We selected most pathways NDOR1 participated on our site, such as Cytosolic iron-sulfur cluster assembly,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDOR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | COX6A1,CYP2U1,HPSE,DBH,SULT1C2,LYPLA1,ARSJ,IVD,CYP3C4,AMDHD1 |
| Cytosolic iron-sulfur cluster assembly | CIAO1,MMS19,CIAPIN1,NUBP1,FAM96B,NUBP2 |
Protein Function
NDOR1 has several biochemical functions, for example, FMN binding,NADP binding,NADPH-hemoprotein reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDOR1 itself. We selected most functions NDOR1 had, and list some proteins which have the same functions with NDOR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| flavin adenine dinucleotide binding | TXNRD2,MAOB,CRY-DASH,NOS3,MTHFR,FMO2,AIFM4,ACAD11,ACADS,DLDH |
| FMN binding | NOS2,MTRR,POR,NOS2A,NOS2B,TYW1,TYW1B,NOS1,DHODH,PNPO |
| iron ion binding | CYP2C55,CYP2N13,CYP2C8,HIF1AN,CYP2P10,MSMO1,CYP7A1A,NOS1,CYP19A1,CYP2F1 |
| protein binding | GPS2,SARM1,GCG,TAB1,RASGRP3,MRPL23,GRB7,E4F1,CALD1,MAGEH1 |
| NADP binding | HMGCRA,ASPDH,SPR,CRYM,G6PD,PGD,ME1,CRYZL1,NNT,H6PD |
| oxidoreductase activity | CYP8B2,C10orf33,AKR1A1B,ETFDH,ALDH3A2A,GFOD2,CYP2F2,CYP46A1.3,IYD,CYP2K17 |
| NADPH-hemoprotein reductase activity | NOS2,MTRR,POR,CYP2J6,NOS2B,NOS3,NOS2A,NOS1 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | CYP2E1,CYP11A1,MICAL1,CYP11B1,MICAL2,COQ6,MTRR,CYP4F18,POR,CYP11B2 |
Interacting Protein
NDOR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDOR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDOR1.
TCF4;MTUS2;EFHC2;CIAPIN1;TCHP
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