NAV2
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Official Full Name
neuron navigator 2 -
Overview
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
NAV2;neuron navigator 2;FLJ10633;FLJ11030;FLJ23707;HELAD1;helicase;APC down regulated 1;KIAA1419;POMFIL2;pore membrane and/or filament interacting like protein 2;RAINB1;retinoic acid inducible gene in neuroblastoma 1;5330421F07Rik;AU067780;mKIAA3015;RAINB2;Helicase, APC down regulated 1;mCG 145366;NAV 2;Retinoic acid inducible in neuroblastoma 1;Steerin 2;STEERIN2;Unc 53 homolog 2;Unc53H2;steerin-2;unc-53 homolog 2;helicase, APC down-regulated 1;pore membrane and/or filament-interacting-like protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NAV2-1199H | Recombinant Human NAV2, His-tagged | E.coli | Human | His | C-term-350 | |
| NAV2-1170HCL | Recombinant Human NAV2 cell lysate | Human | Non |
|
Involved Pathway
NAV2 involved in several pathways and played different roles in them. We selected most pathways NAV2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NAV2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NAV2 has several biochemical functions, for example, ATP binding,helicase activity,heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NAV2 itself. We selected most functions NAV2 had, and list some proteins which have the same functions with NAV2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAD2L1BP,RUVBL1,SPRR2A,LHX4,PDS5A,IGFL1,DTD2,ITGB1BP2,KIAA1143,EIF3J |
| helicase activity | DDX58,ANXA1,DICER1,DDX39AA,DHX58,DDX52,EIF4A1A,BAT1,HELZ,SMARCAL1 |
| ATP binding | HSPA1B,IP6K1,MYO5B,DDX50,CLPB,HSPD1,STK3,NSFA,ATAD5,ACTG1 |
| heparin binding | VEGFA,SLIT3,FGFBP1,FGF12,FGFRL1,COL20A1,PLA2G2D,SAA1,F11,TENM1 |
Interacting Protein
NAV2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAV2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NAV2.
PIAS2;ING5;CFAP58;ADAT2;RBM15B;RBM15B
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References
- Cohen-Dvashi, H; Ben-Chetrit, N; et al. Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression. EMBO MOLECULAR MEDICINE 7:299-314(2015).
- Abe, T; Yamazaki, D; et al. The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway. DEVELOPMENT 141:4716-4728(2014).
