NAT
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Official Full Name
N-acetyltransferase -
Overview
N-acetyltransferase is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2 -
Synonyms
NAT;N-acetyltransferase;AANAT;Arylalkylamine N acetyltransferase;SNAT;ARD1A;ARD1 homolog A, N-acetyltransferase (S. cerevisiae);GNPNAT1;glucosamine-phosphate N-acetyltransferase 1;HGSNAT;heparan-alpha-glucosaminide N-acetyltransferase;MAK10;MAK10 homolog, amino-acid N-acetyltransferase subunit (S. cerevisiae);NAT1;N-acetyltransferase 1 (arylamine N-acetyltransferase);NAT2;N-acetyltransferase 2 (arylamine N-acetyltransferase);NAT5;N-acetyltransferase 5 (GCN5-related, putative);NAT6;N-acetyltransferase 6 (GCN5-related);NAT8;N-acetyltransferase 8 (GCN5-related, putative);NAT8L;N-acetyltransferase 8-like (GCN5-related, putative);NAT9;N-acetyltransferase 9 (GCN5-related, putative);NAT10;N-acetyltransferase 10 (GCN5-related);NAT11;N-acetyltransferase 11 (GCN5-related, putative);NAT12;N-acetyltransferase 12 (GCN5-related, putative);NAT13;N-acetyltransferase 13 (GCN5-related);NAT14;N-acetyltransferase 14 (GCN5-related, putative);NAT15;N-acetyltransferase 15 (GCN5-related, putative)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NAT-3656C | Recombinant Chicken NAT, His-tagged | E.Coli or Yeast | Chicken | His | 287 |
|
| NAT-7074C | Recombinant Chicken NAT | Mammalian Cell | Chicken | His |
|
Involved Pathway
NAT involved in several pathways and played different roles in them. We selected most pathways NAT participated on our site, such as Caffeine metabolism,Drug metabolism - other enzymes,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Caffeine metabolism | NAT2,CYP1A2,NAT1,PNAT10,PNAT3,CYP2A6,UOX,XDH,Nat3 |
| Drug metabolism - other enzymes | XDH,UGT1A4,Nat3,NAT1,UPP1,UGT1A6A,UGT1A6B,TPMT,CES2,UGT1A6 |
| Metabolic pathways | MAN1A1,ST8SIA5,SUCLA2,AOX2P,GALNTL4,CHDH,GNSA,ABP1,PDHA2,PMVK |
Protein Function
NAT has several biochemical functions, for example, arylamine N-acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAT itself. We selected most functions NAT had, and list some proteins which have the same functions with NAT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| arylamine N-acetyltransferase activity | Nat3,AANAT,PNAT3,NAT2,PNAT10 |
Interacting Protein
NAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAT here. Most of them are supplied by our site. Hope this information will be useful for your research of NAT.
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