NAPRT1
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Official Full Name
nicotinate phosphoribosyltransferase domain containing 1 -
Overview
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007). -
Synonyms
NAPRT1;nicotinate phosphoribosyltransferase domain containing 1;nicotinate phosphoribosyltransferase;PP3856;FHIP;FHA HIT interacting protein;NAPRTase;Nicotinic acid phosphoribosyltransferase;FHA-HIT-interacting protein;nicotinate phosphoribosyltransferase domain-containing protein 1
Recombinant Proteins
- Mouse
- Rat
- Chicken
- Human
- Mammalian Cell
- HEK293
- Yeast
- E.coli
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NAPRT1-10426M | Recombinant Mouse NAPRT1 Protein | Mammalian Cell | Mouse | His |
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| NAPRT1-3902R | Recombinant Rat NAPRT1 Protein | Mammalian Cell | Rat | His |
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| NAPRT1-7104C | Recombinant Chicken NAPRT1 | Mammalian Cell | Chicken | His |
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| NAPRT1-1165HCL | Recombinant Human NAPRT1 cell lysate | Human | Non |
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| NAPRT1-3561R | Recombinant Rat NAPRT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| NAPRT1-3561R-B | Recombinant Rat NAPRT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| NAPRT1-5476H | Recombinant Human NAPRT1 protein, His-tagged | Yeast | Human | His | 229-538aa |
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| NAPRT1-5908M | Recombinant Mouse NAPRT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NAPRT1-5908M-B | Recombinant Mouse NAPRT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| NAPRT1-677H | Recombinant Human NAPRT1 Protein (229-538 aa), GST-tagged | E.coli | Human | GST | 229-538 aa |
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Involved Pathway
NAPRT1 involved in several pathways and played different roles in them. We selected most pathways NAPRT1 participated on our site, such as Nicotinate and nicotinamide metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAPRT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CYP4A10,MAOA,GAD2,DHRS4L2,DGKD,HMGCL,GGT6,NMRK1,ATP5H,GAL3ST1A |
| Nicotinate and nicotinamide metabolism | AOX4,NADKA,ENPP1,NT5C1AA,BST1,NT5C,NT5C3A,NNT,AOX3L1,NMNAT3 |
Protein Function
NAPRT1 has several biochemical functions, for example, ligase activity,nicotinate phosphoribosyltransferase activity,nicotinate-nucleotide diphosphorylase (carboxylating) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAPRT1 itself. We selected most functions NAPRT1 had, and list some proteins which have the same functions with NAPRT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | UBE2L3A,CMTM2A,RNF43,ZSWIM2,RNF182,RNF152,ATG3,UBE2F,NEDD4,RNF144AA |
| protein binding | C3orf39,RERG,TRADD,CCNK,SERPINB3C,SH3PXD2B,ALDOB,PDK3,WDR48,JAK3 |
| nicotinate-nucleotide diphosphorylase (carboxylating) activity | NAMPTB,NAPRT,QPRT,KCNG4,NAMPT |
| nicotinate phosphoribosyltransferase activity | NAPRT,KCNG4 |
Interacting Protein
NAPRT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAPRT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NAPRT1.
RBPMS;GRAMD3;IGBP1
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