LZTS1
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Official Full Name
leucine zipper, putative tumor suppressor 1 -
Overview
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. -
Synonyms
LZTS1;leucine zipper, putative tumor suppressor 1;F37/Esophageal cancer related gene coding leucine zipper motif;leucine zipper putative tumor suppressor 1;FEZ1;F37;F37/esophageal cancer-related gene-coding leucine-zipper motif;LZTS1_HUMAN;Psdzip70
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LZTS1-676H | Recombinant Human LZTS1, His-tagged | E.coli | Human | His | C-200aa | |
| LZTS1-3525R | Recombinant Rat LZTS1 Protein | Mammalian Cell | Rat | His |
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| LZTS1-460H | Recombinant Human LZTS1 Protein, His-tagged | E.coli | Human | His |
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| LZTS1-9418M | Recombinant Mouse LZTS1 Protein | Mammalian Cell | Mouse | His |
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| LZTS1-4574HCL | Recombinant Human LZTS1 293 Cell Lysate | HEK293 | Human | Non |
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| LZTS1-3181R | Recombinant Rat LZTS1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| LZTS1-3181R-B | Recombinant Rat LZTS1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| LZTS1-4522H | Recombinant Human LZTS1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| LZTS1-5283M | Recombinant Mouse LZTS1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LZTS1-5283M-B | Recombinant Mouse LZTS1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LZTS1 involved in several pathways and played different roles in them. We selected most pathways LZTS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LZTS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
LZTS1 has several biochemical functions, for example, DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LZTS1 itself. We selected most functions LZTS1 had, and list some proteins which have the same functions with LZTS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | YBX1,ZNF222,NPAS4A,ASXL2,STRA13,HOXA4A,PRRXL1,PPARAA,ZFP746,MESP1 |
| transcription factor activity, sequence-specific DNA binding | GATA2A,KAT7A,FOXA2,ZEB1,RAB11FIP4A,ZNF548,GATAD1,RXRBA,ZNF577,FOSL1 |
| protein binding | RRM2,LOC780933,PEX14,ZNF436,CCNA2,FOXB1,HTN1,STXBP3,DOCK4,DFFA |
Interacting Protein
LZTS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LZTS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LZTS1.
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