LUC7L2
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Official Full Name
LUC7-like 2 (S. cerevisiae) -
Overview
This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. -
Synonyms
LUC7L2;LUC7-like 2 (S. cerevisiae);putative RNA-binding protein Luc7-like 2;CGI 59;CGI 74;CGI 74 protein;FLJ10657;H_NH0792N18.3;hLuc7B2;LUC7B2;LC7L2_HUMAN;LUC7 like 2 (S. cerevisiae);Putative RNA binding protein Luc7 like 2;CGI-59;CGI-74
Recombinant Proteins
- Human
- Chicken
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LUC7L2-1168H | Recombinant Human LUC7L2 | Mammalian Cell | Human | His |
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| LUC7L2-2456C | Recombinant Chicken LUC7L2 | Mammalian Cell | Chicken | His |
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| LUC7L2-4606HCL | Recombinant Human LUC7L2 293 Cell Lysate | HEK293 | Human | Non |
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| LUC7L2-3404H | Recombinant Human LUC7L2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| LUC7L2-3404H-B | Recombinant Human LUC7L2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| LUC7L2-4582H | Recombinant Human LUC7L2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| LUC7L2-6217HF | Recombinant Full Length Human LUC7L2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 391 amino acids |
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Involved Pathway
LUC7L2 involved in several pathways and played different roles in them. We selected most pathways LUC7L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LUC7L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LUC7L2 has several biochemical functions, for example, enzyme binding,mRNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LUC7L2 itself. We selected most functions LUC7L2 had, and list some proteins which have the same functions with LUC7L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mRNA binding | FXR2,PAIP2,EIF4ENIF1,SNRNP35,TPR,CELF4,NUDT21,RC3H2,EIF4A1,RPS5 |
| enzyme binding | SRC,CYP2C8,HIST1H2AG,FOXO4,PLCB1,HIST1H2AL,NOXA1,CYP1A2,PEX5,ACAT1 |
| protein binding | KRT80,PKM2,EFHC1,VANGL1,PIK3R1,ZNF3,CSF1,BRSK1,PTBP1,MAGEA11 |
| poly(A) RNA binding | RPS3A,BTF3,FUBP3,RTCD1,SMNDC1,IMP3,RPL19,BST2,HNRNPA0,POLRMT |
Interacting Protein
LUC7L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LUC7L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LUC7L2.
MAP1LC3B;YWHAG;NFYA;SRSF6;SRSF7;APPBP2;GADD45G;CEP126
Resources
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References
- Hosono, N; Makishima, H; et al. Spliceosomal Gene LUC7L2 Mutation Causes Missplicing and Alteration Of Gene Expression In Myeloid Neoplasms. BLOOD 122:-(2013).
- Vandell, AG; McDonough, CW; et al. Hydrochlorothiazide-induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study. JOURNAL OF INTERNAL MEDICINE 276:486-497(2014).
