LTN1
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Official Full Name
listerin E3 ubiquitin protein ligase 1 -
Overview
Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 (PubMed 19196968)). -
Synonyms
LTN1;listerin E3 ubiquitin protein ligase 1;C21orf10, C21orf98, chromosome 21 open reading frame 98 , ring finger protein 160 , RNF160, zinc finger protein 294 , ZNF294;E3 ubiquitin-protein ligase listerin;FLJ11053;KIAA0714;LISTERIN;ri
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LTN1-9355M | Recombinant Mouse LTN1 Protein | Mammalian Cell | Mouse | His |
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| LTN1-5241M | Recombinant Mouse LTN1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LTN1-5241M-B | Recombinant Mouse LTN1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LTN1 involved in several pathways and played different roles in them. We selected most pathways LTN1 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| presentation | FBXO27,ASB2,RNF4,B2ML,RNF182,UBR1,RNF25,UBE2L6,HUWE1,FBXO17 |
| Immune System | CD96,GBP2,LAIR2,FCN3,KLC3,IGHM,ERAP2,CD200R4,KLRB1F,DUSP3B |
| Antigen processing: Ubiquitination & | ATG7,SPSB4,UBE2J2,UFL1,FBXO17,TRIM39,NPEPPS,LRR1,TRIM63,HUWE1 |
| Adaptive Immune System | AP2S1,RNF34,PJA2,KIF26A,RNF4,TPP2,TREML2,WWP1,ARIH2,ITPR2 |
| Class I MHC mediated antigen processing & | RNF41,SEC23A,LRRC41,UBE2J2,KLHL21,CYBA,LRSAM1,FBXO17,SPSB1,SPSB2 |
| Proteasome degradation | ASB6,UBE2U,TRIM50,ATG7,FBXO27,HECTD3,TRIM11,UBE2E3,IWS1,PJA2 |
Protein Function
LTN1 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTN1 itself. We selected most functions LTN1 had, and list some proteins which have the same functions with LTN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein-glutamic acid ligase activity | NEURL3,UBE2IB,NEURL1B,G2E3,HERC2,MARCH6,RNF149,SIAH2L,RAG1,HECW2 |
| protein-glycine ligase activity, initiating | NEURL1B,DTX1,MARCH11,MYLIPA,MARCH9,UBE2IA,TTLL3,RNF169,NEURL3,MARCH6 |
| zinc ion binding | SF1,TRIM35-39,RORC,DBF4B,TRPS1,ZNF638,ZFAND5,FBXO30,ZFP259,PDXK |
| tubulin-glutamic acid ligase activity | TTLL1,MARCH11,RNF144AB,ARIH1L,MARCH9,RNF187,UBR1,RFWD2,HECW2,NEURL3 |
| ligase activity | TRIP12,TTLL13,TTLL9,SIAH2,TRIM71,UBE2IA,RNF114,DTX1,TTLL4,TTLL11 |
| metal ion binding | APTX,LOXL2A,TET3,CLPX,IKBKG,TGM2B,ALOX12E,SMPD2,CDC7,FDX1B |
| protein-glycine ligase activity, elongating | SIAH1A,RNF187,MUL1A,G2E3,RFWD2,MARCH5L,HERC2,UBE2IB,ARIH1L,SHRPRBCK1R |
| ribosomal S6-glutamic acid ligase activity | TMEM129,TRIM41,SHRPRBCK1R,RAG1,NEURL3,NEURL1B,MYLIPB,ITCHA,SIAH2L,DTX1 |
| coenzyme F420-2 alpha-glutamyl ligase activity | RAG1,ZNRF2B,MARCH9,RNF144AB,SIAH1A,RNF169,HERC2,TMEM129,TRIM50,SIAH2L |
Interacting Protein
LTN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTN1.
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