LTB4R2
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Official Full Name
leukotriene B4 receptor 2 -
Overview
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. -
Synonyms
LTB4R2;leukotriene B4 receptor 2;BLT2;NOP9;BLTR2;JULF2;KPG_004;LTB4-R2;LTB4-R 2;LTB4 receptor JULF2;leukotriene B4 receptor BLT2;seven transmembrane receptor BLTR2
Recombinant Proteins
- Rat
- Mouse
- Human
- Mus musculus
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- His&Fc&Avi
Involved Pathway
LTB4R2 involved in several pathways and played different roles in them. We selected most pathways LTB4R2 participated on our site, such as Calcium signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTB4R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | EDNRB,P2RX4,P2RX3,GNA15.4,NOS2A,PRKCBA,ATP2B3B,MYLK4,GRIN1,PLCD1A |
| Neuroactive ligand-receptor interaction | CSH2,S1PR5,CHRNB4,TAAR11,ADRA2DB,LPAR2,F2RL2,OXTR,NPFFR2.1,GZMA |
Protein Function
LTB4R2 has several biochemical functions, for example, G-protein coupled peptide receptor activity,leukotriene B4 receptor activity,leukotriene receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTB4R2 itself. We selected most functions LTB4R2 had, and list some proteins which have the same functions with LTB4R2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| leukotriene receptor activity | LTB4R,CYSLTR2,CYSLTR1 |
| leukotriene B4 receptor activity | LTB4R |
| G-protein coupled peptide receptor activity | CYSLTR1,LTB4R,GRPR,MC1R,GPR37L1,RXFP3.2B,RXFP3,CYSLTR2,NPR1,RXFP4 |
Interacting Protein
LTB4R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTB4R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTB4R2.
AKT1
Resources
Research Area
Granulocyte MarkersBasophils
Eosinophils
Neutrophils
B Cell Chemotaxis, Migration, and Adhesion
T Cell Migration
CD Antigen (Granulocyte Markers)
Dendritic Cell Activation
Related Services
Related Products
References
- Guerrero, ATG; Verri, WA; et al. Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE(2). JOURNAL OF LEUKOCYTE BIOLOGY 83:122-130(2008).
- Yan, Y; Wang, BX; et al. Inhibitory effects of mizolastine on ultraviolet B-induced leukotriene B4 production and 5-lipoxygenase expression in normal human dermal fibroblasts in vitro. PHOTOCHEMISTRY AND PHOTOBIOLOGY 82:665-669(2006).
