LRTOMT
-
Official Full Name
leucine rich transmembrane and 0-methyltransferase domain containing -
Overview
This gene encodes two different proteins. One is a leucine-rich transmembrane protein of unknown function while the other is an O-methyltransferase. Defects in the O-methyltransferase protein can cause nonsyndromic deafness. Several transcript variants encoding different isoforms of each protein have been found for this gene. -
Synonyms
LRTOMT;leucine rich transmembrane and 0-methyltransferase domain containing;deafness, autosomal recessive 63 , DFNB63, leucine rich repeat containing 51 , LRRC51;leucine-rich repeat-containing protein 51;transmembrane O-methyltransferase;COMT2;tran
Recombinant Proteins
- Rhesus macaque
- Rat
- Zebrafish
- Chicken
- Human
- Pan troglodytes
- Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
- Macaca mulatta
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- His&Fc&Avi
- GST
- Myc&DDK
Involved Pathway
LRTOMT involved in several pathways and played different roles in them. We selected most pathways LRTOMT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LRTOMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LRTOMT has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LRTOMT itself. We selected most functions LRTOMT had, and list some proteins which have the same functions with LRTOMT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
LRTOMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRTOMT here. Most of them are supplied by our site. Hope this information will be useful for your research of LRTOMT.
Resources
Related Services
Related Products
References
- Riahi, Z; Bonnet, C; et al. Whole Exome Sequencing Identifies New Causative Mutations in Tunisian Families with Non-Syndromic Deafness. PLOS ONE 9:-(2014).
- Charif, M; Bounaceur, S; et al. The c.242G > A mutation in LRTOMT gene is responsible for a high prevalence of deafness in the Moroccan population. MOLECULAR BIOLOGY REPORTS 39:11011-11016(2012).
