LRRC2
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Official Full Name
leucine rich repeat containing 2 -
Overview
This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2. -
Synonyms
LRRC2;leucine rich repeat containing 2;leucine-rich repeat-containing protein 2
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LRRC2-9255M | Recombinant Mouse LRRC2 Protein | Mammalian Cell | Mouse | His |
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| LRRC2-4645HCL | Recombinant Human LRRC2 293 Cell Lysate | HEK293 | Human | Non |
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| LRRC2-2689H | Recombinant Human LRRC2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Lrrc2-3825M | Recombinant Mouse Lrrc2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| LRRC2-4680H | Recombinant Human LRRC2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| LRRC2-5176M | Recombinant Mouse LRRC2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LRRC2-5176M-B | Recombinant Mouse LRRC2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| LRRC2-5948HF | Recombinant Full Length Human LRRC2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 371 amino acids |
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| LRRC2-610H | Recombinant Human LRRC2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
LRRC2 involved in several pathways and played different roles in them. We selected most pathways LRRC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LRRC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
LRRC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LRRC2 itself. We selected most functions LRRC2 had, and list some proteins which have the same functions with LRRC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
LRRC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRRC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRRC2.
b4dyc6_human;TP53RK
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References
- Kim, HY; Kim, SJ; et al. Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion. FEBS Journal 282:259-270(2015).
- Nakamori, M; Takahashi, T; et al. Molecular Markers for Granulovacuolar Degeneration Are Present in Rimmed Vacuoles. PLOS ONE 8:-(2013).
