LRP4
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Official Full Name
low density lipoprotein receptor-related protein 4 -
Synonyms
CLSS;LRP-4;LRP10;MEGF7;SOST2
Recombinant Proteins
- Human
- Mouse
- CHO
- Mammalian Cell
- E.coli
- Yeast
- HEK293
- Non
- His
- His&GST
- His&Fc&Avi
- GST
Involved Pathway
LRP4 involved in several pathways and played different roles in them. We selected most pathways LRP4 participated on our site, such as ECM proteoglycans,Extracellular matrix organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Extracellular matrix organization | FURINA,EFEMP2,ADAMTS18,MMP11,BMP1A,COL3A1,COL17A1A,MFAP1B,COL17A1,LTBP4 |
| ECM proteoglycans | COMP,MATN3,ITGB3A,ASPN,DAG1,MATN3B,MATN1,ACAN,COL9A3,MUSK |
Protein Function
LRP4 has several biochemical functions, for example, apolipoprotein binding,calcium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP4 itself. We selected most functions LRP4 had, and list some proteins which have the same functions with LRP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GORASP1,STK36,TMEM194,FAM69A,MLLT1,DOT1L,TTLL10,XRCC6,ARPM1,GAPDH |
| apolipoprotein binding | LPA,MAPT,LPL,PLG,VLDLR,LRP6,SCARB1,LRP1,CANX,ABCA1 |
| protein homodimerization activity | CARD9,FZD1,PITX2,GRPEL2,PDCD10,DGCR8,QPRT,RAB11FIP4B,CBX1,NAGA |
| calcium ion binding | NRXN1,CRB2B,CALUA,ATP2A1,PCDH2G3,PLSCR2,TNNC1,CDH12,THBS3,S100G |
| receptor tyrosine kinase binding | PTPN14,TRP53,NRG3,FIZ1,ANGPT2A,MYOC,DOCK4,GAS6,GNB2L1,NRG1 |
| scaffold protein binding | CHUK,CAV2,CIT,NLRP1,ADCY6,KRT5,TREM2,VIM,DLG4,SCN5A |
Interacting Protein
LRP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP4.
SOST;rpoB;DFNB31;ARRB1;EXOSC5
Resources
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References
- Ha, JC; Richman, DP; et al. Myasthenia gravis and related disorders: Pathology and molecular pathogenesis. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:651-657(2015).
- Katarzyna, MZ; Belaya, K; et al. Collagen Q - A potential target for autoantibodies in myasthenia gravis. JOURNAL OF THE NEUROLOGICAL SCIENCES 348:241-244(2015).
