LRIG1
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Official Full Name
leucine-rich repeats and immunoglobulin-like domains 1 -
Overview
Leucine-rich repeats and immunoglobulin-like domains protein 1 is a protein that in humans is encoded by the LRIG1 gene.It encodes a transmembrane protein that has been shown to interact with receptor tyrosine kinases of the EGFR-family, METand RET. -
Synonyms
LRIG1;leucine-rich repeats and immunoglobulin-like domains 1;leucine-rich repeats and immunoglobulin-like domains protein 1;DKFZP586O1624;leucine rich repeat protein LRIG1;LIG 1;LIG1;ortholog of mouse integral membrane glycoprotein LIG 1;Leucine rich repeat protein;leucine rich repeats and immunoglobulin like domains 1;LIG-1;LRIG1_HUMAN;OTTHUMP00000213345;OTTHUMP00000213346;leucine-rich repeat protein LRIG1;ortholog of mouse integral membrane glycoprotein LIG-1
Recombinant Proteins
- Mouse
- Cynomolgus
- Human
- HEK293
- C-His
- Human Cell
- HEK293T
- Mammalian cells
- E.coli
- His
- Non
- Myc&DDK
- His&Fc&Avi
- Flag
- His&T7
Involved Pathway
LRIG1 involved in several pathways and played different roles in them. We selected most pathways LRIG1 participated on our site, such as Signal Transduction,Signaling by EGFR, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRIG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | PDK4,DEPDC7,ARHGAP17,PROKR1,MDK,CCNT2B,KIDINS220B,WIPF3,ARHGAP36,TLE4 |
| Signaling by EGFR | ADAM12,PAG1,SPRY1,PTPRK |
Protein Function
LRIG1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by LRIG1 itself. We selected most functions LRIG1 had, and list some proteins which have the same functions with LRIG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
LRIG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRIG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRIG1.
Resources
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References
- Oh, YM; Lee, SB; et al. USP8 modulates ubiquitination of LRIG1 for Met degradation. SCIENTIFIC REPORTS 4:-(2014).
- Poulin, EJ; Powell, AE; et al. Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine. STEM CELL RESEARCH 13:422-430(2014).
