LPIN2

  • Official Full Name

    lipin 2

  • Overview

    Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance.

  • Synonyms

    LPIN2;lipin 2;phosphatidate phosphatase LPIN2;KIAA0249;lipin-2

Recombinant Proteins

  • Chicken
  • Mouse
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • His
  • Non
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
LPIN2-1528C Recombinant Chicken LPIN2 Mammalian Cell Chicken His
LPIN2-9203M Recombinant Mouse LPIN2 Protein Mammalian Cell Mouse His
LPIN2-4667HCL Recombinant Human LPIN2 293 Cell Lysate HEK293 Human Non
LPIN2-2996H Recombinant Human LPIN2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Lpin2-3811M Recombinant Mouse Lpin2 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
LPIN2-5142M Recombinant Mouse LPIN2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
LPIN2-5142M-B Recombinant Mouse LPIN2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    LPIN2 involved in several pathways and played different roles in them. We selected most pathways LPIN2 participated on our site, such as Glycerolipid metabolism,Glycerophospholipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPIN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid metabolism CDS2,LPCAT1,LPGAT1,STIL,PTDSS1,DGKZ,PLA2G16,PLD2,LPCAT4,EPT1
    Metabolic pathways GALNT14,IVD,OLAH,ATP5G3,GCNT4,RDH12,GALM,TGDS,GK2,AGPHD1
    Glycerolipid metabolism MOGAT3,DGKD,AKR1A1B,DGAT2,MOGAT3A,LPIN1,AGPAT6,PPAP2B,DGAT1A,PPAP2C

    Protein Function

    LPIN2 has several biochemical functions, for example, phosphatidate phosphatase activity,transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LPIN2 itself. We selected most functions LPIN2 had, and list some proteins which have the same functions with LPIN2. You can find most of the proteins on our site.

    Function Related Protein
    transcription coactivator activity TCF3,GABPA,HTATIP2,BRCA1,NR1H3,TAF5L,SERTAD2,HAND1,MTF1,ING4
    phosphatidate phosphatase activity STIL,LPIN3,PPAP2B,PPAP2CB,LPIN1,PPAPDC1A,LPPR3,LPPR2,PPAP2A,PPAP2C

    Interacting Protein

    LPIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPIN2.

    PPP1CA;gcvT

    Resources

    Research Area

    Phosphatases and Regulators

    References

    • Herlin, T; Fiirgaard, B; et al. Efficacy of anti-IL-1 treatment in Majeed syndrome. ANNALS OF THE RHEUMATIC DISEASES 72:410-413(2013).

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