LPCAT3
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Official Full Name
lysophosphatidylcholine acyltransferase 3 -
Synonyms
C3F;LPCAT;LPSAT;OACT5;nessy;MBOAT5;LPLAT 5
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- His&Fc&Avi
Involved Pathway
LPCAT3 involved in several pathways and played different roles in them. We selected most pathways LPCAT3 participated on our site, such as Glycerophospholipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPCAT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid metabolism | GPD1B,PHOSPHO1,LCAT,PLA2G2D,PLA2G3,PPAP2CB,TAE1,ETNK1,PLA2G15,ETNK2 |
Protein Function
LPCAT3 has several biochemical functions, for example, 1-acylglycerophosphocholine O-acyltransferase activity,2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity,2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LPCAT3 itself. We selected most functions LPCAT3 had, and list some proteins which have the same functions with LPCAT3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-acylglycerophosphocholine O-acyltransferase activity | LPCAT2,LPCAT4,TAZ,LPCAT1 |
| N-acyltransferase activity | MBOAT7,Acnat1,HRASLS5,DGAT2L6,CML2,BAAT,CML5,MBOAT4,HHAT,ACNAT2 |
| C-acyltransferase activity | NAT14,HHAT,MBOAT4,MBOAT7,Acnat1,DGAT2L6,MBOAT1,ACNAT2,CML5,CML2 |
| N-palmitoyltransferase activity | NAT14,CML2,HHAT,ACNAT2,MBOAT1,Acnat1,MBOAT4,CML5,MBOAT7,DGAT2L6 |
| O-succinyltransferase activity | MBOAT4,DGAT2L6,CML5,HHAT,NAT14,CML2,MBOAT7,Acnat1,ACNAT2,MBOAT1 |
| S-acetyltransferase activity | DGAT2L6,CML2,NAT14,CML5,Acnat1,MBOAT4,HHAT,MBOAT1,ACNAT2,MBOAT7 |
| UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity | MBOAT1,NAT14,MBOAT4,HHAT,ACNAT2,Acnat1,CML2,CML5,DGAT2L6,MBOAT7 |
| transferase activity | ACVR1L,KMT2A,WBP7,SRPK1A,PDK2B,PAK2B,UBE2D2A,ZDHHC20A,IGF1RA,DGAT1A |
| peptidyl-lysine N6-myristoyltransferase activity | CML5,DGAT2L6,ACNAT2,CML2,HHAT,NAT14,MBOAT4,MBOAT1,MBOAT7,Acnat1 |
Interacting Protein
LPCAT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPCAT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LPCAT3.
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References
- Tintle, N. L.; Pottala, J. V.; et al. A genome-wide association study of saturated, mono- and polyunsaturated red blood cell fatty acids in the Framingham Heart Offspring Study. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 94:65-72(2015).
- Zarini, Simona; Hankin, Joseph A.; et al. Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells. PROSTAGLANDINS & OTHER LIPID MEDIATORS 113:52-61(2014).
